Vázquez TY, Infante VM, Miranda GO, Vázquez TYC, Vázquez AH, Torres SC, Verdasquera CD

Language: Spanish
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ABSTRACT

Introduction: Tests for antibodies to the hepatitis C virus in blood donors have been used to identify patients and it is an important element in disrupting transmission by this route.
Objective: The objective of the present investigation was to describe the behavior of the detection of anti-HVC in Artemisa municipality between 2006-2010 years and to identify the main clinical alterations in the patients with positive RNA detection test.
Methods: An ecological study of time series was carried out. The universe was 162 patients resident in Artemisa municipality, to whom, in blood donations, they were detected positivity for anti-HCV according to the ELISA method (UMELISA). The information was obtained through the database of the Territorial Blood Bank of San Antonio de los Baños between January 1, 2006 and December 31, 2010.
Results: In this period 8057 blood donations were made; 2.01 % were positive. The seasonal behavior, the cyclical variation of the chronological series and an increasing tendency were demonstrated. The months of September, June and November were identified as months with highest incidence. The male-to-female ratio was 13: 1, with male sex predominating among anti-HVC positive donors with 94.7 %. Nucleic acid of C virus was detected by liver biopsy in 41 cases between 41 and 45 years old predominantly. The 95.1 % of the patients presented normal transaminases, a history of percutaneous instrumentation and histological changes compatible with chronic hepatitis at the time of diagnosis.
Conclusions: The usefulness of anti-HVC screening for the planning of health resources in the territory and for the identification of patients with different degrees of liver injury, despite being asymptomatic and with normal transaminases, is confirmed.