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2017, Number 2

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Rev Esp Med Quir 2017; 22 (2)

Toxic effects of manganese

Ramírez AR, Azcona-Cruz MI

Language: Spanish
References: 39
Page: 71-75
PDF size: 927.75 Kb.


ABSTRACT

Manganese (Mn) is a trace element required in small quantities for growth, development, and function of human beings, but in excess it can be a potent neurotoxicant. It is a normal constituent of air, soil, water, and food; Mn is also used in a wide variety of other products, including: fireworks, dry-cell batteries, fertilizer, paints, medical imaging agents, cosmetics, and it may also be used as an additive in gasoline. The primary way you can be exposed to Mn is by eating food such as grains, beans, and nuts or manganese-containing nutritional supplements. The occupational risk factor increases in steel foundry workers or welders who may have high levels of Mn in their blood. It has been reported that the Mn neurotoxicity is associated with motor and cognitive disturbances known as Manganism. The mechanisms underlying these toxic condition remain unknown, Manganism causes clinical signs and symptoms resembling, but not identical to, Parkinson’s disease.


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