Gómez VN, Gamayo CY, González EL, Olivera LIR, Ruiz GD

Language: Spanish
References: 0
Page: 85-96
PDF size: 153.43 Kb.

ABSTRACT

Introduction: Myasthenia gravis is a chronic disease of the neuromuscular junction, it is autoimmune by nature and it is recognized that thymectomy is an effective therapeutic modality in this clinical entity.
Objectives: Clinically characterize the myasthenic thymectomized patients.
Methods: A retrospective, descriptive, observational study was conducted in the Neurology Service at Hermanos Ameijeiras Surgical Clinical Hospital from January 1984 to December 2014.
Results: 393 patients were recruited; the majority was female and aged 30-39 years. 65.3%of them had grade II b of disease intensity. Thymic hyperplasia (66.9%) was the most common histological alteration of the thymus. Hyperthyroidism was the most frequent autoimmune disease. The myasthenic crisis represented the main postoperative complication and it essentially showed in patients with thymoma. Mortality was 1.3%.
Conclusions: Grade II b disease intensity was more common, the histological type of thymic hyperplasia and mortality was low.