Calderín BRO, Yanes QMÁ, Yanes QM, Jiménez PR, Fernández-Britto RJE, León ÁJL, Bacallao GJ

Language: Spanish
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ABSTRACT

Introduction: The insulin resistance syndrome describes a group of related clinical abnormalities that occur more commonly in subjects with insulin resistance and compensatory hyperinsulinemia.
Objective: To identify the sensitivity and specificity of the new diagnostic classification of insulin resistance syndrome, ACUSIR, to identify the frequency of insulin resistance and the insulin resistance syndrome in dyslipidemic patients.
Methods: Descriptive and cross-sectional study in 344 patients with dyslipidemia aged 15-85 years who repeatedly attended the internal medicine clinic of Hermanos Ameijeiras Hospital. Patients with primary dyslipidemia, alcoholism, drugs that alter insulin sensitivity, endocrinopathies, hepatopathies and nephropathies, stress, obstructive apnea, secondary hypertension were excluded. All patients underwent the oral glucose tolerance test (OGTT), fasting insulinemia, cholesterol, triglycerides, and high density lipoprotein-cholesterol. Waist-hip index, waist circumference, body mass index, blood pressure, and the HOMA index were measured. The IR criterion was the same as the HOMA index (≥ 2.6).
Results: The frequency of insulin resistance was high in dyslipidemic patients, 258 patients (75 %). The ACUSIR classification has a high sensitivity (75 %) and a high specificity (86 %) to detect IR in dyslipidemic patients (p= 0.000).
Conclusions: The ACUSIR classification has good sensitivity and specificity to identify insulin resistance in dyslipidemic patients. Insulin resistance is associated with dyslipidemia.