medigraphic.com
ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología

2017, Number 4

<< Back Next >>

Rev Latin Infect Pediatr 2017; 30 (4)

Virus and bacteria identified by PCR in children with community-acquired pneumonia

Villa-Alanis N, Iglesias-Leboreiro J, Bernárdez-Zapata I, Silva-Ramírez H, Rendón-Macías ME

Language: Spanish
References: 17
Page: 151-157
PDF size: 272.38 Kb.


ABSTRACT

Objective: To analyze the agents identified by molecular studies of naso-oropharyngeal secretions in children with community-acquired pneumonia (CAP) and the therapeutic actions. Material and methods: Patients without co-morbidities between 1m to 16y with bronchopneumonia, lobar pneumonia, interstitial pneumonia or complicated pneumonia. With or without rapid test for influenza and RSV and/or PCR viral and/or bacterial. Treatment and changes to some identification was analyzed. Results: 187 patients (94 women), 94 (50.2%) bronchopneumonia, 90 (48.1%) lobar pneumonia two interstitial pneumonia and complicated with pleural effusion. A 107 (57.3%) underwent a molecular test. 80/107 (74.7%) with identification of at least one agent), in 56/80 (70%) single virus, in 18/80 (22.5%) virus and bacteria, and 6 (7.5%) only bacteria. In 26/80 (32.5%) had some modification to treatment. Conclusions: When looking for molecular identification of an infectious agent in CAP, this was high (≈75%), with predominance of virus alone or in co-infection; but with low impact on therapeutic decisions.


REFERENCES

  1. Marcdante KJ, Kliegman RM, Jenson HB, Behrman RE. Nelson pediatría esencial. 6a edición. España: Editorial Elsevier; 2011. pp. 398-403.

  2. Diagnóstico y tratamiento de la neumonía adquirida en la comunidad en las/los pacientes de 3 meses a 18 años en el primero y segundo nivel de atención. México: Instituto Mexicano del Seguro Social; 1 de diciembre de 2015. Disponible en: http://www.cenetec.salud.gob.mx/descargas/gpc/CatalogoMaestro/120_GPC_NEUMONIA/Neumonia_ninos_evr_cenetec.pdf

  3. Neuman MI, Monuteaux MC, Scully KJ, Bachur RG. Prediction of pneumonia in a pediatric emergency department. Pediatrics. 2011; 128 (2): 246-253.

  4. Metlay JP, Kapoor WN, Fine MJ. Does this patient have community-acquired pneumonia? Diagnosing pneumonia by history and physical examination. JAMA. 1997; 278 (17): 1440-1445.

  5. Gereige RS, Laufer PM. Pneumonia. Pediatr Rev. 2013; 34 (10): 438-456; quiz 455-456.

  6. Durbin WJ, Stille C. Pneumonia. Pediatr Rev. 2008; 29 (5): 147-158; quiz 159-160.

  7. Mohamed KE, Wahb OA, Ibragim SA. Radiological findings in severe pneumonia in children 1-59 months in a children´s hospital, Khartoum, Sudan. Pediatr Therapeut. 2012; 2 (3): 1-3.

  8. Florin TA, French B, Zorc JJ, Alpern ER, Shah SS. Variation in emergency department diagnostic testing and disposition outcomes in pneumonia. Pediatrics. 2013; 132 (2): 237-244.

  9. Williams DJ, Hall M, Shah SS, Parikh K, Tyler A, Neuman MI et al. Narrow vs broad-spectrum antimicrobial therapy for children hospitalized with pneumonia. Pediatrics. 2013; 132 (5): e1141-e1148.

  10. Rothrock S1, Green SM, Fanelli JM, Cruzen E, Costanzo KA, Pagane J. Do published guidelines predict pneumonia in children presenting to an urban ED? Pediatr Emerg Care. 2001; 17 (4): 240-243.

  11. Centers for Disease Control and Prevention (CDC). Pediatric bacterial meningitis surveillance - African region, 2002--2008. MMWR Morb Mortal Wkly Rep. 2009; 58 (18): 493-497.

  12. Vuori-Holopainen E, Peltola H. Reappraisal of lung tap: review of an old method for better etiologic diagnosis of childhood pneumonia. Clin Infect Dis. 2001; 32 (5): 715-726.

  13. Bradley JS, Byington CL, Shah SS, Alverson B, Carter ER, Harrison C et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011; 53 (7): e25-e76.

  14. Goodman DC. Unwarranted variation in pediatric medical care. Pediatr Clin North Am. 2009; 56 (4): 745-755.

  15. Hersh AL, Shapiro DJ, Pavia AT, Shah SS. Antibiotic prescribing in ambulatory pediatrics in the United States. Pediatrics. 2011; 128 (6): 1053-1061.

  16. Kronman MP, Hersh AL, Feng R, Huang YS, Lee GE, Shah SS. Ambulatory visit rates and antibiotic prescribing for children with pneumonia, 1994-2007. Pediatrics. 2011; 127 (3): 411-418.

  17. Protocolo de vigilancia basado en laboratorio de influenza y otros virus respiratorios. Instituto Nacional de Salud. Versión 1.0 2007: 1-18. [Consultado 14 de marzo del 2014].




2020     |     www.medigraphic.com