Rangel-Hernández M, Ordóñez-García R

Language: Spanish
References: 16
Page: 36-42
PDF size: 144.44 Kb.

ABSTRACT

The tumoral pathology of the nasal cavity and the paranasal sinuses are unified by the narrow anatomical relation between these structures, that in many cases difficult the exact location of the origin place. Pathologically, the nasal and paranasal sinuses tumors are divided in epithelial and nonepithelial, and both are subdivided as well in benign and malignant. The most frequent benign neoplasia is nasal papiloma. The malignant tumors of nose and paranasal sinuses constitute 1% of all malignant neoplasias of the organism, and near 3% of the originating ones of upper respiratory tract; most frequent is squamous cell carcinoma. With such antecedents, a observational study was made, cross-sectional, retrospective, descriptive and opened that included patients with nasal and paranasal sinuses tumors that taken care in National Medical Center “20 de Noviembre” between January 1994 and December 2002. It was excluded from the study patients with diagnosis of mucocele, polyposis and fibrous displasia; 247 patients participated altogether who fulfilled the inclusion criteria, 96 women (39%) and 151 men (61%) with average age of 45 years. Of them, 85 (34.4%) displayed benign tumors, 160 (64.7%) malignant tumors, and two (0.8%) had coexistence of benign and malignant tumors. Most frequent tumor was the squamous cell carcinoma (28.3%), followed by juvenile nasopharyngeal angiofibroma (12.1%). The patients with nasal and paranasal sinuses tumors appear with nonspecific symptoms that can correspond to any pathology of inflammatory type, nasal obstruction, nasal bleeding and symptoms of sinusitis due to the obstruction.

REFERENCES

1. Bailey BJ. Neoplasms of nose and paranasal sinus. En: Bailey BJ (ed.) Head and neck surgery otolaryngology. Lippincott, Williams and Wilkins, Philadelphia, 3rd ed., 2001; pp. 1267-78.

2. Rice DH. Endonasal approaches for sinonasal and nasopharyngeal tumors. Otolaryngol Clin North Am 2001; 34 (6): 1087-93.

3. Cummings CW. Neoplasms of the nasal cavity and neoplasms of paranasal sinus. En: Cummings CW. Otolaryngology head and neck surgery. Mosby, St. Louis, 3rd. ed., 1998; pp. 883-1134.

4. Durden DD, Williams DW 3rd. Radiology of skull base neoplasms. Otolaryngol Clin North Am 2001; 34 (6): 1043-64.

5. Richardson MS. Pathology of skull base tumors. Otolaryngol Clin North Am 2001; 34 (6): 1025-42.

6. Bales C, Kotapka M, Loevner LA, et al. Craniofacial resection of advanced juvenile nasopharyngeal angiofibroma. Arch Otolaryngol Head Neck Surg 2002; 128 (9): 1071-8.

7. Anthony R. Factors in the pathogenesis of tumors of the sphenoid and maxillary sinuses: a comparative study. Laryngoscope 2000; 110 (10, Suppl 86): S1-38.

8. Calderon G. L. Malignant neoplasms of the nasal cavity and paranasal sinuses: a series of 256 patients in Mexico City and Monterrey. Is air pollution the missing link? Otolaryngol Head Neck Surg 2000; 122 (4): 499-508.

9. Shah J. Cancer of the nasal cavity and paranasal sinuses. En: Decken BC (ed.). Cancer of head and neck. American Cancer Society. New York, 2001; pp. 104-224.

10. Dulguerov P, Allal AS, Calcaterra TC. Esthesioneuroblastoma: a meta-analysis and review. Lancet Oncol 2001; 2 (11): 683-90.

11. Gorelick J, Ross D, Marentette L, Blaivas M. Sinonasal undifferentiated carcinoma: case series and review of the literature. Neurosurgery 2000; 47 (3): 750-4.

12. Knott PD, Gannon FH, Thompson LD. Mesenchymal chondrosarcoma of the sinonasal tract: a clinicopathological study of 13 cases with a review of the literature. Laryngoscope 2003; 113 (5): 783-90.

13. Thompson LD, Miettinen M, Wenig BM. Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. Am J Surg Pathol 2003; 27 (6): 737-49.

14. Nayak LM, Deschler DG. Lymphomas. Otolaryngol Clin North Am 2003; 36 (4): 625-46.

15. Majumdar S, Raghavan U, Jones NS. Solitary plasmacytoma and extramedullary plasmacytoma of the paranasal sinuses and soft palate. J Laryngol Otol 2002; 116 (11): 962-5.

16. Myers LL, Nussenbaum B, Bradford CR, et al. Paranasal sinus malignancies: an 18-year single institution experience. Laryngoscope 2002; 112 (11): 1964-9.