2017, Number 1
Study of a window period documented by nucleic acid technique
Benítez-Arvizu G, Franco-Gómez NE, Flores-Sánchez I, Ojeda JJ, Moreno-Alcantar R
Language: Spanish
References: 8
Page: 18-21
PDF size: 170.05 Kb.
ABSTRACT
Currently with the development of molecular biology techniques it is possible to detect evidence infections through the genome of the agent even before it can be evidenced by serological tests, this has reduced the window period in the detection of infections in consequence increasing transfusion safety avoid transfusion transmissible diseases. In this paper we exposed the detection of one window period for hepatitis B, showing the infection by nucleic acid technology (NAT) before to seroconversion, which is documented trough blood donor following. The implementation of this technology in the blood banks has increased transfusion safety and decreased the risk of transmission of infections across transfusion.REFERENCES
Vermeulen M, Van Drimmelen H, Coleman C, Mitchel J, Reddy R, Lelie N. A mathematical approach to estimate the efficacy of individual-donation and minipool nucleic acid amplification test options in preventing transmission risk by window period and occult hepatitis B virus infections. Transfusion. 2014; 54 (10): 2496-2504.