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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2017, Number 2

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Bol Clin Hosp Infant Edo Son 2017; 34 (2)

Molusco Contagioso en niños: nuevo tratamiento tópico con base en dimetilsulfóxido combinado con yodopovidona

Rodríguez-García R, Rodríguez-Silva R

Language: Spanish
References: 25
Page: 144-150
PDF size: 170.35 Kb.


ABSTRACT

Molluscum contagiosum is a viral infectious disease of the skin caused by a poxvirus. Multiple treatments have been used for this infection with conflicting results. A new combination of topical application has been used with promising results, combined dimethylsulfoxide with povidone iodine. We report the case of a 14-month-old boy who presented MC lesions after the topical application of steroids in the bilateral inguinal region. To treat it, a chemical solution of dimethylsulfoxide combined with iodopovidone was applied, lesions remitted in three weeks. The combination of dimethyl sulfoxide and topically applied iodopovidone in the treatment of MC in this case was successful.


REFERENCES

  1. McCollum AM, Holman RC, Hughes CM, et al. Molluscum contagiosum in a pediatric American Indian population: incidence y risk factors. PLoS ONE. 2014; 9: e103419. doi: 10.1371/journal.pone.103419.

  2. Zhuang K, Xu F, Ran Y, Lama J. Atypical Infantile genital Molluscum Contagiosum. An Bras Dermatol. 2015; 90: 403-5.

  3. Guan H, Nuth M, Zhukovskaya N, et al. A novel target and approach for identifying antivirals against Molluscum Contagiosum virus. Antimicrob Agents Chemother. 2014; 58: 7383-9.

  4. Jawade S, Chugh V, Gohil S, Mistry A, Umrigar D. A clinico-etiological study of dermatoses in pediatric age group in tertiary health care center in South Gujarat region. Indian J Dermatol. 2015; 60: 635. doi: 10.4103/0019-5154.169147.

  5. Casanova JM, Sanmartín V, Soria X, Baradad M, Martí RM, Font A. Dermatosis infantiles en la consulta de dermatología de un hospital general universitario en España. Actas Dermosifiliogr. 2008; 99: 111-8.

  6. Roye R, Meléndez M, Ruiz G, Gamboa A, Morantes J. Enfermedades dermatológicas en la edad pediátrica. Dermatol Venez. 2006; 44: 12-16.

  7. Pérez MMA, Cano RE, Sánchez OMT, Castro LE, Jiménez BF, Hueso MC. Factores de riesgo relacionados con las infecciones de transmisión sexual. Rev Esp Sal Púb. 2017; 91: 201701012.

  8. Monteagudo B, Cabanillas M, Acevedo A, et al. Molusco contagioso: estudio descriptivo. An Pediatr (Barc). 2010; 72: 139-42.

  9. Marsal JR, Cruz I, Teixido C, et al. Efficacy and tolerance of the topical application of potassium hydroxide (10% and 15%) in the treatment of Molluscum Contagiosum: randomized clinical trial; research protocol. BMC Infect Dis. 2011; 11: 278. doi: 10.1186/1471-2334-11- 278.

  10. Chathra N, Sukumar D, Bhat R, et al. A comparative study of 10% KHO solution and 5% imiquimod cream for the treatment of Molluscum Contagiosum in the pediatric age group. Indian Dermatol Online J. 2015: 6: 75- 80.

  11. Coloe Dosal J, Stewart PW, Lin JA, Williams CS, Morrell DS. Cantharidin for the treatment of Molluscum Contagiosum: A prospective, double blinded, placebo- controlled trial. Pediatr Dermatol. 2014; 31: 440-49.

  12. Chularojanamontri L, Tuchinda P, Kulthanan K, Manuskiatti W. Generalized molluscum contagiosum in an HIV patient treated with diphencyprone. J Dermatol Case Rep. 2010; 4: 60-2.

  13. Loyo ME, Zapata G, Santana G. Molusco contagioso: evaluación de diversas modalidades terapéuticas. Dermatol Venez. 2003: 41: 25-8.

  14. Afsar FS, Erkan CD, Karaca S. Clinical practice trends in cryosurgery: a retrospective study of cutaneous lesions. Postep Derm Alergol. 2015; 32: 88-93.

  15. Capriotti K, Stewart K, Pelletier J, Capriotti J. Molluscum Contagiosum viral infection treated with a dilute povidone-iodine/dimethylsulfoxide preparation. Dermatol Ther. 2016; 6: 101-103.

  16. Pelletier JS, Stewart KP, Capriotti K, Capriotti JA. Rosacea blepharoconjunctivitis treated with a novel preparation of dilute povidone iodine and dimethylsulfoxide: a case report and review of de literature. Ophthalmol Ther. 2015; 4: 143-50.

  17. Capriotti K, Capriotti JA. Onychomycosis treated with dilute povidone-iodine/ dimethyl sulfoxide preparation. Int Med Case Rev J. 2015; 8: 231-33.

  18. Capriotti K, Stewart KP, Pelletier JS, Capriotti J. A novel topical 2% povidone-iodine solution for the treatment of common warts: a randomized, double-blind, vehicle- controlled trial. Dermatol Ther. 2015; 5: 247-52.

  19. Capriotti K, Capriotti J. Chemotherapy-associated paronychia treated with a dilute povidone-iodine/dimethylsulfoxide preparation. Clin Cosmet Investig Dermatol. 2015; 8: 489-91.

  20. Lázaro GA, García FM. Corticosteroides tópicos. Inf Ter Sist Nac Salud. 2010; 34: 83-8.

  21. Sánchez SL, Sáenz AE. Antisépticos y desinfectantes. Dermatol Peru. 2005; 15: 82-103.

  22. Capriotti K, Capriotti JA. Dimethyl sulfoxide: history, chemistry, and clinical utility in dermatology. J Clin Aesthet Dermatol. 2012; 5: 24-26.

  23. García J. Efecto del dimetilsulfóxido en la respuesta quimioluminiscente y el consumo de oxígeno de neutrófilos humanos activados. Rev Costarric Cienc Med. 2001; 22: 17-32.

  24. Alamar R, Olaya V. Dermatitis de contacto por dimetil sulfóxido. Enferm Dermatol. 2012; 16: 42-44.

  25. Capriotti K, Capriotti JA. Topical iodophor preparations: chemistry, microbiology, and clinical utility. Dermatol Online J. 2012; 18: 1.




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