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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2017, Number 2

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Bol Clin Hosp Infant Edo Son 2017; 34 (2)

Tumor de GIST pediátrico. Presentación de dos casos y revisión de la literatura

Morales PA, Millán VLO, Covarrubias EG, Galván RVG, Ríos GCG, Larios FTC

Language: Spanish
References: 29
Page: 127-135
PDF size: 833.77 Kb.


ABSTRACT

Gastrointestinal Stromal Tumors (GIST) are mesenchymal neoplasms originating in the Interstitial Cells of Cajal. It has an annual incidence of 0.02 per million inhabitants, with a predisposition for the female. They occur after the fourth decade of life, however, there are reports of these tumors in pediatric patients and young adults. They are usually located in the stomach (50-60%). Pediatric GISTs have large clinical-pathological and molecular differences of their adult counterpart. The most frequent presenting symptoms are anemia, abdominal distension and pain, vomiting and digestive tract bleeding. Two cases of GIST were presented whose initial manifestation was anemic syndrome. The tumors were located in the stomach and both were completely resected. At the moment they are one and two years old in surveillance.


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