Hernández GY, Alcalá VT, López SMV

Language: Spanish
References: 9
Page: 395-401
PDF size: 343.61 Kb.

ABSTRACT

Introduction: The Histoplasmosis is an endemic illness that presents an opportunist behavior in which causal germ is the Histoplasma capsulatum (HC), considered a dimorphic mushroom. Objective: To present a case with the diagnosis of Generalized Histoplasmosis in which pharyngeal manifestations were the beginning of the illness. Presentation of the case: The case of a patient is presented with the pharyngeal symptoms that were the first manifestation of the illness, in which the biopsy allowed to arrive to the diagnostic. Later the patient presented other manifestations with clinical-microbiologic aspects of progressive dissemination. Conclusions: The pharyngeal Histoplasmosis is an uncommon systemic mycosis and with a difficult diagnostic, it is necessary a good interrogation and physical exam, in those patients with factors of risk of infectious illnesses without apparent diagnosis and progressive deterioration of their general state.

REFERENCES

1. Fernández CM, Illnait Zaragozi MT, Martínez G, Mayada R, Perurena MR, Monrroy VE. Una actualización acerca de histoplasmosis. Rev cubana med. Trop. 2011; 63(3):189-205.

2. González VE, Fernández CM, Rivero Figueroa D. Aspectos epidemiológicos, clínicos, microbiológicos y terapéuticos de la histoplasmosis. Rev. Cub. de medicina militar.2013; 42(1):94-105.

3. Fernández CM, Martínez G, Illnait Zaragozi MT, Mayada RP, González L. Brotes de histoplasmosis ocupacional en la provincia de La Habana. Rev cub med. 2010; 62(1):68-72.

4. Trombetha LA, Vaca de Soto AJ. Diagnóstico de la histoplasmosis diseminada asociada al SIDA. Rev Cub de med. Trop. 2013; 65(1): 137-143.

5. Monrroy VE, Martínez G, Fernández CM, Illnait Zaragozi MT, García A, Perrurena M. Diagnóstico molecular de histoplasmosis diseminada en pacientes cubanos con SIDA. Rev. Cub. de med. Trop. 2014; 66(1):120-131.

6. Pérez AD, Gala González A, Rodríguez ME, Capó de Paz V, Collazo S, Fernández Abreu C. Histoplasmosis con manifestaciones cutáneas en pacientes VIH-SIDA. Rev cub. Med. Trop. 2007; 59 (2):119-26.

7. Fernández CM, Corral Varona C, Martínez G, Rodríguez ME, Ruiz Pérez A. Histoplasmosis diseminada progresiva en pacientes con SIDA. Rev. Cub. Med. Trop. 1996. 48 (3).

8. Xavier ME, Fernández CM, Díaz Rodríguez R, Martínez Machín G, Illnait Zaragozi MT, Perurena M. Evaluación de cuatro métodos de extracción del ADN de Histoplasma capsulatum y su uso en reacción del PCR. Vaccimonitor. 2014; 23 (2). 49-56.

9. Fernández CM, Martínez León A, Echevarría Y, Martínez Machín G, et al. Sesibilidad in vitro de Histoplasma capsulatumvar. Frente a anfotericina B, Ketokonazol, Itrakonazol y Fluconazol. Rev. Cub. Med. Trop. 2003; 5(2):76-82.