Gutiérrez-Salgado JE, Argüelles CJA, González MMG, Gutiérrez GY

Language: Spanish
References: 10
Page: 158-162
PDF size: 111.97 Kb.

ABSTRACT

Toxic epidermal necrolysis syndrome is an uncommon, acute, life-threatening disorder. This is induced by medication and has a reported mortality rate of 20 to 60 percent. This syndrome is a severe mucocutaneous reaction and can affect any percentage of the body area. Two cases are reported and the importance of early diagnosis and treatment is pointed out. Most of these cases are more severe than the primary illnesses. The first patient is a woman in her forties with a biliary tract injury. She developed epidermal necrolysis syndrome after being treated with antibiotics. Her treatment was based on human immunoglobulin and covering the skin with cultured keratinocites. She evolved satisfactorily. The second case is a female patient in her fifties who was being treated with anticonvulsives due to neurocisticercosis. She developed the syndrome five days before she was admitted. This patient died. Both patients required treatment in an intensive care unit.

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