De la Osa-Busto M, Reyes-Hernández KL, Reyes-Gómez U, Perea-Martínez A, Luévanos-Velázquez A, Hernández-Lira I, Sandoval-García MS, Zempoalteca-Sánchez E, Saavedra-Cabrera SL, Avila-Correa A

Language: Spanish
References: 22
Page: 161-167
PDF size: 594.23 Kb.

ABSTRACT

Th e streptococci pneumonia or pneumococci still been a most frequent cause of child infection, most of all acquired pneumonia in the community Objetive: Know the antimicrobial sensitivity in children in an hospital of second level of attention. Material and methods: qualitative, quantitative, prospective, comparative study to antimicrobials of solitude of strains of SP obtained in the period of January 1, 2012 to January 31, 2015. Results: in the analysis of 47 strains of SP from them 27(57.44%) women and 20(42.56%) men. Analyzing the ages it observe more incidents in child of 0 days to 11 months 17(36.17%); 1 year to 1 year 11 months 17(36.17%); From the strains obtained, sensitive to Ciprofl oxacin 47(100%), Penicillin 43 (91.48%), Cefaloticin 42 (89.36%), Cefazolinicin 40 (85.10%), Amoxicillin 38 (80.85%), Oxacilinicin 37 (78.72%), Tetracycline’s 37 (78.72%), Rifampicin 34 (72.34%), Clindamycin 31 (65.95%) the intermedian was Norfl oxacin 26 (55.31 %), Ampicillin 25 (53.19 %) y Erythromycin 24 (51.06%). Present high resistance to Impanel 36 (76.59%), Nitrofuroantoin 36 (76.59%) y Gentamicin 28 (59.57%). Conclusion: Th e pneumococci in our medium has a high sensitivity to Ciprofl oxacin, penicillin, cefalotin, cefazolin, amoxicillin, and a low sensitivity to gentamicin and intermediate to Ampicillin and Erythromycin.

REFERENCES

1. Yadav MK, Go YY, Chae SW, Song JJ. Th e Small Molecule DAM Inhibitor, Pyrimidinedione, Disrupts Streptococcus pneumoniae Biofi lm Growth In Vitro. PLoS One. 2015 Oct 2;10(10):e0139238. doi: 10.1371/journal.pone.0139238. eCollection 2015. PubMed PMID: 26431532; PubMed Central PMCID: PMC4592238

2. Gonçalves MT, Mitchell TJ, Lord JM. Immune ageing and susceptibility to Streptococcus pneumoniae. Biogerontology. 2015 Oct 15. [Epub ahead of print] PubMed PMID: 26472172

3. Pichichero ME, Khan MN, Xu Q. Next generation protein based Streptococcus pneumoniae vaccines. Hum Vaccin Immunother. 2015 Nov 5:0. [Epub ahead of print] PubMed PMID: 26539741.

4. Hosseini SM, Poorolajal J, Karami M, Ameri P. Prevalence of Nasopharyngeal Carriage of Streptococcus pneumonia in Iran: A Meta-Analysis. J Res Health Sci. 2015 Summer;15(3):141-6. PubMed PMID: 26411658

5. Torres N, Velázquez R, Mercado EH, Egoavil M, Horna G, Mejía L. et al. Resistencia antibiótica de streptococcus pneumoniae en portadores nasofaríngeos sanos de siete regiones del Perú. Rev Peru Med Exp Salud Publica [Internet]. 2013 Dec [cited 2015 Nov 10]; 30( 4 ): 575-582

6. Alfataye MS, Ruiz GJ, Sánchez SM, Guerrero GC, Sensibilidad de Streptococcus Pneumoniae en niños portadores sanos en Murcia (España) Anales de Pediatría 2015; 83(3): 183-90

7. Soto NA, Echániz AG, Barajas CN, Arredondo GJ, Tinoco FJ, Anzures GA. Streptococcus Pneumoniae causante de infección en infantes menores de 60 días de edad: serotipos y suceptibilidad antimicrobiana. XXXIII Congreso Interamericano de Infectología Pediátrica de la Asociación Mexicana de Infectología Pediátrica Monterrey 2014.

8. Tomasz A. Multiple-antibiotic-resistant pathogenic bacteria. N Engí J Med 1994; 330: 1.247-1.2515

9. http://www.who.int/mediacentre/factsheets/fs331/es/

10. Noda AA, Vidal TLA, Vidal TJI, Streptococcus pneumoniae, mechanisms of antimicrobial resistance, artículo de revisión Rev. Cuba Pediatr 2011; 83(3): 288-95

11. OMS 2013 Pneumonia Fact sheet N°331 Reviewed November 2013

12. De Egea V, Muñoz P, Valerio M, de Alarcón A, Lepe JA, Miró JM, et al. GAMES Study Group. Characteristics and Outcome of Streptococcus pneumoniae Endocarditis in the XXI Century: A Systematic Review of 111 Cases (2000-2013). Medicine (Baltimore). 2015 Sep;94(39):e1562.

13. Pallares R, Gudiol F, Linares J, Ariza J, Rufí G, et al. Risk factors and response to antibiotic therapy in adults with bacteremic pneumoniea caused by penicillin-resistant pneumococci. N Engl J Med 1987; 317:18-22. 17.

14. Bouza E. Infección neumocócica. Patrones de susceptibilidad antibiótica en España. Rev Enfer Infecc Microbiol Med 1993; 11 (SupiI):15-22

15. Mamishi S, Moradkhani S, Mahmoudi S, Hosseinpour-Sadeghi R, Pourakbari B Penicillin-Resistant trend of Streptococcus pneumoniae in Asia: A systematic review. Irán J Microbiol. 2014 6 (4): 198-210.

16. Kim SH, Canción JH , Chung DR , Th amlikitkul V, Yang Y, Wang H, Lu M, et al. Grupo de Estudio ANSORP Evolución de la resistencia a los antimicrobianos y los serotipos de Streptococcus pneumoniae en los países asiáticos: una Red Asiática para la vigilancia de patógenos resistentes estudio (ANSORP). Antimicrob Agents Chemother. 2012 Mar; 56 (3): 1418-26.

17. Obando I, Sánchez TD, Molina QA, Delgado PI, Porras A, Morillo GB, et al. Epidemiología de la colonización nasofaríngea por Streptococcus pneumoniae en niños menores de 6 años de la ciudad de Sevilla Enferm Infecc Microbiol Clin. 2011; 29(8): 581–6

18. Torres N, Velásquez R, Mercado HE, Egovail M, Horna G, Mejia L, et al. Resistencia antibiótica de streptococcus pneumoniae en portadores nasofaríngeos sanos de siete regiones del Perú Rev Peru Med Exp Salud Pub 2013; 30 (4): RME

19. Manresa F. El neumococo resistente Editorial Arch Bronconeum 2016: 33: 367-368

20. Linares J, Alonso T, Pérez JL, Domínguez MA, Pallares R, Martín R. Decreased susceptibility of penicillin-resistant pneumococci to twenty-four beta-lactam antibiotics. Joumal of Antimicrobial Chemotherapy 1992; 30: 279-288.

21. Gold HS, Moellering RC. Antimicrobial-Drug resistance. N Engí J Med 1996; 333: 1.445-54

22. Tinoco JC. La neumonía neumocócica y su prevención mediante una vacuna resultados del estudio CAPITA El residente 2015;10(2): 52.7