2017, Number 4
Characterization, by magnetic resonance, of medulloblastomas and histopathological correlation
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Language: Spanish
References: 20
Page: 276-285
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ABSTRACT
Background: the ideal method to diagnose medulloblastomas is magnetic resonance. Radiological characteristics, age, sex, and customary localization have been studied before. The diagnosis may be underestimated in atypical presentations.Objetives: correlate characteristics by magnetic resonance and histopathological lineage. Identify age, sex, and localization of presentation in a given time
Statistical Analysis: tables of frequency were made to classify patients’ age and sex, and medulloblastoma localizations. For radiological and histopathological correlation χ2 and Spearman’s correlation were used.
Material and Method: 21 magnetic resonances from patients with diagnosis of medulloblastoma at Hospital General de México in the period from January 2013 through January 2016 were examined. the variables evaluated were: age, sex, medulloblastoma localization, histopathological report, and radiological characteristics.
Results: of 29 pathological diagnoses of medulloblastoma, 21 magnetic resonance studies were examined: 9 adults (seven between 21 and 39 years of age and two over 40 years of age) and 12 persons under 21 years of age; 16 were men (7 ‹ 21 years of age, 9 › 21 years of age) and 5 women (4 ‹ 21 years of age and one 24 years of age). The primary localization was infratentorial, with supratentorial extension in two cases. Of the infratentorial tumors, five were in the vermis, seven in the right cerebral hemisphere, five in the left cerebral hemisphere, and two in the tentorium. The most common radiological characteristics were solid appearance, heterogeneous enhancement, and lobulated edges.
Conclusions: The usual age of onset of medulloblastomas is before 21 years, but we found two patients over 40. The most typical localization is infratentorial and the percentage of supratentorial extension is low. They show a predilection for the male gender. The radiological characteristics were similar in all the study cases, and we identified no significant correlation between radiological characteristics and histological lineage.
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