2017, Number 10
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Ginecol Obstet Mex 2017; 85 (10)
Prevalence of thyroid autoimmunity in subfertile women
Hinojosa-Rodríguez KA, Martínez-Cruz N, Ortega-González C, López-Rioja MJ, Recio-López Y, Sánchez-González CM
Language: Spanish
References: 23
Page: 694-704
PDF size: 555.11 Kb.
ABSTRACT
Objetive: To estimate the prevalence of autoimmune thyroid disease
in subfertile patients who come to the Human Reproduction service
of the National Institute of Perinatology Isidro Espinosa de los Reyes,
Mexico city.
Material and Methods: A retrospective, cross-sectional, observational,
ambispective study evaluating 18- to 43-year-old women from
the INPer "Isidro Espinosa de los Reyes" human reproduction service
with a thyroid profile determination with anti-thyroid antibodies in
The first consultation of infertility.
Results: The prevalence of TEE in the population of infertile women
is 19%. 48% have seropositivity for Ac-TPO, 32% for Ac-tiroglobulina
plus Ac-TPO and the remaining 20% only for Ac-tiroglobulina. A
prevalence of clinical hypothyroidism of 8% and subclinical of 48%
was observed in the group of patients with ATE. The mean TSH for
women with ATE was 4.6 µUI/L. Women with isolated euthyroid ETA
represent 8.3% of the population and have a high rate of previous
spontaneous abortions (45.5%) as well as failure in assisted reproduction
techniques (70%).
Conclusion: Determination of thyroid autoimmunity should be
routinely performed in the female population.
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