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2017, Number 2

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Rev Cuba Endoc 2017; 28 (2)

Vitamin D and its relationship with some elements of the metabolic syndrome in middle-aged population

Acosta CA, Barreto PLC, Díaz SC, Domínguez AE, Navarro DD, Cabrera GM, García GY

Language: Spanish
References: 33
Page: 1-13
PDF size: 161.92 Kb.


ABSTRACT

Introduction: Vitamin D deficiency or insufficiency is a world pandemic affecting roughly 1 billion people. Several research studies reveal that Vitamin D has as a non-classical function its role in cardiovascular diseases and in the metabolic syndrome.
Objectives: to determine whether there is Vitamin D deficiency in the middle-aged population and its possible association with some elements of the metabolic syndrome.
Methods: descriptive and cross-sectional study of 17 men and 42 women conducted from August 2014 to April 2016. The levels of 25-hydroxyl Vitamin D (normal ≥ 30, deficiency < 30 ng/mL), were also determined and linked to clinical and biochemical elements of the metabolic syndrome.
Results: in the group, 47.46 % presented with Vitamin D deficiency. The mean was reduced in obese people (29.36 ng/mL). Significant inverse correlation was found (p= 0.039) between the increased waist circumference in women and the Vitamin D levels. Significant positive correlation (p= 0.015) was also observed when levels of diastolic blood pressure were associated in persons with systolicdiastolic blood hypertension with levels of Vitamin D. In the group, 62.5% of obese persons had Vitamin D deficiency. The mean comparison between levels of Vitamin D and higher levels of glycemia was statistically significant (p= 0.013).
Conclusions: Vitamin D deficiency was common in the studied persons. Increased waist circumference in women is associated with lowest levels of Vitamin D whereas higher levels of Vitamin D are associated with higher diastolic blood pressure values. Vitamin D deficiency is related to higher levels of glycemia.


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