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ISSN 1028-4818 (Electronic)

2017, Number 5

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Mul Med 2017; 21 (5)

Cellular immune response in children with malaria. General Hospital Luanda, Angola, 2015

Borrero TCM, Maso ZME

Language: Spanish
References: 21
Page: 655-665
PDF size: 109.69 Kb.


ABSTRACT

Introduction: malaria is a severe parasitic disease caused by sporozoites of the genus Plasmodium; it is more severe in children. Objective: to identify alterations of cellular immune response in children with malaria Method: a descriptive observational study of the behavior of the peripheral blood cell values of 26 hospitalized children in Ward A of the General Hospital of Luanda between May 12 and 17, 2015. Results: predominantly male sex (60%), neutrophil and lymphocyte cellular response and hemoglobin levels are directly related to higher percentage in low range; 50% of the children with low neutrophil numbers had the same positive and negative results according to the complementary thick drop; in the children where lymphocytes were decreased, Plasmodium positivity was found in dense gout (71.4%). Conclusion: malaria predominated in male children aged 7 to 9 months, who were characterized by low numbers of lymphocytes, neutrophils and hemoglobin. There were no differences between the positivity of the thick drop associated with low neutrophil titers, children infected with malaria who have low lymphocyte titers express greater positivity in the Plasmodium results in the thick drop and have worse prognosis.


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