Paz SCE, Albán MCJ, Rodríguez DCD

Language: Spanish
References: 0
Page: 600-612
PDF size: 124.33 Kb.

ABSTRACT

Introduction: vertical transmission is the most common way of transmitting the HIV virus during the perinatal period. Without any intervention, an estimated 20 % of infants will become infected before birth. Objective: to evaluate vertical transmission prevention treatment by measuring the effectiveness, adherence and safety of antiretroviral treatment in a Public Hospital of Babahoyo-Ecuador. Method: a descriptive study was performed on all HIV-positive pregnant women treated at the Martin Icaza Hospital in Babahoyo during the period 2014 to 2015. The variables measured were program effectiveness, as demonstrated by the number of HIV-positive newborns; adherence to treatment and safety of antiretroviral treatment demonstrated by reporting adverse effects, changes in hematological / hepatic profiles, CD4 lymphocyte count, and viral load. Results: the main results of the evaluation of 40 cases of pregnant women with HIV with the HAART treatment of: tenofovir + emtricitabine + efavirenz. The efficacy in vertical transmission was 100 %, with 0 cases of infected newborns. Adherence to treatment was 95 %. The regimen used proved to be safe for patients despite a slight significant increase in their liver profiles. In 93 % of pregnant women there were no adverse effects and those that were reported had minor effects: headache and nausea. Conclusions: it was evidenced the protection of HAART avoiding the vertical transmission of pregnant mothers infected by HIV, promoted by their adherence to the treatment and the low occurrence of adverse effects.