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Anales de Radiología México 2017; 16 (3)
Language: Spanish
References: 34
Page: 227-226
PDF size: 1023.50 Kb.
ABSTRACT
Purpose: recognize the CT angiography protocol as the initial diagnostic
method for pulmonary thromboembolism. Correlate the clinical
data which raised suspicion and indication for the study and increase
the accuracy of diagnosis.
Material and Methods: in a first group, 145 studies/128 patients
were reviewed over 3 years (June 2003 through June 2006)
with multidetector tomography (16) and CT angiography protocol
due to suspicion of pulmonary thromboembolism. Interpretations
of the studies, both retrospective and prospective, were provided
by two physicians. Requests submitted were examined to identify
clinical data which raised suspicion, signaling of Wells criteria or
any other criterion establishing the probability of pulmonary thromboembolism;
we analyzed whether it was acute/chronic, central/
peripheral, unilateral/bilateral, associated with pulmonary infarct or
not, association with pleural/pericardial effusion and whether it was
associated with oncological disorders or other predisposing factors. In
a second group, 110 multidetector tomographies (8 and 16) with CT
angiography protocol were reviewed due to suspicion of pulmonary
thromboembolism/venography by tomography, in 98 patients, from
April 2005 to January 2010, including patients who were asked to
submit to the protocol and those in whom, incidentally, without prior
clinical suspicion, pulmonary thromboembolism was identified; we
also reviewed the clinical conditions which gave rise to suspicion,
use of the Wells criteria, and the D-dimer test and analyzed if it was
acute/chronic, central/peripheral, and unilateral/bilateral and if it was
associated with oncological disorders or other predisposing factors.
Results: in the first group, 15 studies/14 patients were excluded, giving
a final total of 130 studies/114 patients. In 81 studies, 78 patients,
results were negative for pulmonary thromboembolism (68.42%). In
49 studies, 36 patients were positive for pulmonary thromboembolism
(31.57%). In 11 patients, pulmonary thromboembolism was classified
as acute, in 7 as chronic and in 15 as acute chronic. In 7 positive patients,
subsequent studies showed persistence and in 5 resolution. In
49 studies, 36 patients were positive for pulmonary thromboembolism
(31.57%). In the second group, of the 110 studies included, 58 were
positive (53%) and 52 negative (47%). Of the studies with positive
results the diagnosis was incidental in 15 (26%). Clinical association
of primary oncological pathology was identified and CT angiography
to detect pulmonary thromboembolism was indicated in 9 cases (8%
of the studies). In 12 (11%) of cases, we identified clinical association
with a recent surgical event, respiratory difficulty, and indication of
CT angiography to detect pulmonary thromboembolism.
Conclusion: pulmonary CT angiography is helpful in identification
and characterization of pulmonary thromboembolism and is the study
of choice with 100% sensiti vity and specificity.
REFERENCES
Matheus TMC, Sandoval ZJ, Criales CJL, Martínez-Guerra ML et al. La tomografía computarizada helicoidal del tórax en el diagnóstico de la tromboembolia pulmonar crónica no resuelta. Arch Inst Cardiol Mex 2000;70(5):456-467.
Goldhaber SZ y Elliot G. Acute pulmonary embolism: Part I: Epidemiology and diagnosis. Circulation 2003;108:2726- 2729.
Goldhaber SZ y Elliot G. Acute pulmonary embolism: Part II: Risk stratification, treatment and prevention. Circulation 2003;108:2834-2838.
Chunilal SD, Eikelboom JW, Attia J, Miniatti M, Panju AA, Simel DL et al. Does this patient have pulmonary embolism? JAMA 2003;290(21):2849-2858.
Hirsh J y Hoak J: Management of deep vein thrombosis and pulmonary embolism. Circulation, 1996;93:2212-2245.
Kriffin W D: The epidemiology of diagnosed pulmonary embolism and deep venous thrombosis in the elderly. Int Med 1994;154: 861.
Segal JB, Eng J, Tamariz LJ, et al. Review of the evidence on diagnosis of deep venous thrombosis and pulmonary embolism. Ann Fam Med 2007;5:63-73.
Marieke J H A, Kruip, Monique, Leclercq, Prins, Büller: Diagnostic strategies for excluding pulmonary embolism in clinical outcome studies. Annals of internal medicine, 2003;138:941-951.
Stein PD, Heles C A: Clinical, Laboratory, roentgenographic, and electrocardiographics in patiens with acute pulmonary embolism and no pre-existing cardiac o pulmonary disease: Chest 1991; 100- 598.
Bounameaux H: Ciralici R Measurement of D- dimer inplasma as diagnostic aid in suspected pulmonary embolism. Lancet 1991;337:196-200.
The Pioped Investigators. JAMA 1990; 263:2753-2759.
Hull RD, Hirsh J. Pulmonar angiography, ventilation lung scanning, and venography for clinically suspected pulmo nar embolism with anormal perfusion scan. Ann Int Med 1983;98:891-899.
Qanadli SD, Hajjam ME, Mesurolle B, Barre O: Pulmonary embolism detection: Prospective evaluation of dual-section helical CT versus selective pulmonary arteriography in 157 patients. Radiology 2000;217(2):447-55.
Perrier A, Howarth N, Didier D, Loubeyre P, Unger PF, de Moerloose P, Slosman D, Junod A, Bounameaux H. Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism. Ann Intern Med 2001;135(2):88-97.
Russo V, Piva T, Lovato L, Fattorri R, Gavelli G. Multidetector CT: A new gold standard in the diagnosis of pulmonary embolism? State of the art and diagnostic algorithms. Radiol Med 2005;109(1-2):49-61.
Rathbun SW, Raskob GE, Whitsett TL: Sensitivity and specificity of helical computed tomography in the diagnosis of pulmonary embolism: a systematic review. Ann Intern Med 2000;132(3):227-32.
Kim KL, Muller NL, Mayo JR: Clinically suspected pulmonary embolism: utility of spiral CT. Radiology 1999;210(3):693-7.
Ciccotosto C, Lawrence R. Goodman LR, Lacey Washington L et al. Indirect CT Venography Following CT pulmonary angiography spectrum of CT findings. JTI 2002;17:18–27.
Quiroz, R, Kucher N, Zou, KH et al. Clinical validity of a negative CT scan in pts with suspected PE. JAMA 2005;293(16):2012-2017.
Scatarige JC, Weiss CR, Diette GB et al. Scanning systems and protocols used during imaging for acute pulmonary embolism. Academic Radiology 2006;13(6):678-685.
Wu AS, Pezullo JA, Cronan JJ, Hou DD y Mayo-Smith WW. CT Pulmonary Angiography: Quantification of pulmonary embolus as a predictor of patient outcome—Initial experience. Radiology 2004;230:831–835.
Brunot S, Corneloup O, Latrabe V et al. Reproducibility of MDST in detection of subsegmental acute PE. Eur Radiol 2005;15:2057-2063
Tapson VF. Acute pulmonary embolism. NEJM 2008;358:1037-1052.
Pengo V, Lensing AWA, Prins MH, Marchiori A, Davidson BL, Tiozzo F et al. Incidence of chronic thromboembolic pulmonary hypertension after pulmonary embolism. NEJM 2004;350:2257-2264.
Washington L y Gulsun M. CT for thromboembolic disease. Curr Probl Diagn Radiol 2003;32:105-126.
Fedullo PF y Tapson VF. The evaluation of suspected pulmonary embolism. NEJM 2003;349:1247-1256.
Perrier A, Roy PM, Sanchez O, Le Gal G, Meyer G, Gourdier AL et al. Multidetector-row CT in suspected pulmonary embolism. NEJM 2005;352:1760-1768.
Wittram C, Maher MM, Yoo AJ, Kalra MK, Shepard JAO, McLoud TC. CT angiography of pulmonary embolism: Diagnostic criteria and causes of misdiagnosis. Radiographics 2004;24:1219-1238.
Elicker BM, Lee TJ y Webb R. Role of multislice tomography of the thorax for the evaluation of suspected pulmonary embolism. Clin Pulm Med 2007;14:157-165.
Saad WEA y Saad N. CT for venous thromboembolic disease. Radiol Clin N Am 2007;45:423-445.
Saénz de la Calzada C, Sánchez-Sánchez V, Velásquez- Martín MT, Tello de Meneses R, Gómez-Sánchez MA, Delgado-Jiménez J: Guías de práctica clínica de la Sociedad Española de Cardiología en tromboembolismo e hipertensión pulmonar. Rev Esp Cardiol 2001;54:194-210.
VillaGómez-Ortiz AJ, Hernández-Silva S, Castro Aldana MS et al. Tromboembolia pulmonar. Acta Médica 2005;3:33 -39.
Bautista R. Zona de Seguridad para trombosis. Médicos de México 2007;69(6):16-18.
Jha S, Ho A, Bhargavan M, Owen JB y Sunshine JH. Imaging evaluation for suspected pulmonary embolism: What do emergency physician and radiologist say? AJR 2010;194:W38-W48.