Calderón DA, García VJ, Cázarez RVD, Alvarado GIO

Language: Spanish
References: 17
Page: 65-69
PDF size: 214.30 Kb.

ABSTRACT

The orthokeratinized odontogenic cyst has been a recognized entity since 1981; it represents a specific group of cysts of odontogenic origin. It is now classified independently from the keratocystic odontogenic tumor. It is a rare, asymptomatic lesion that commonly occurs at an average age of 35.4 years and has a predilection for males. It occurs most frequently in the jaw, mandibular molar region and branch. It is not associated with Gorlin-Goltz syndrome; however, there have been cases where neoplastic transformation in its epithelial layer has been demonstrated. Radiographically, unilocular radiolucency can be observed, which produces an expansion of cortical bone and is generally associated with impacted teeth. Histologically, it has an orthokeratinized epithelium, a prominent granular layer, and cubic basal cells with little tendency to having polarized nuclei. Immunohistochemically, it has little potential for proliferation and cellular activity, which explains their low recurrence after surgery and suggests the use of an alternative conservative treatment. It is a non-aggressive cystic lesion with well-defined characteristics. Treating it early can improve the patient’s prognosis. This is a case report on an 11-year-old female patient, her clinical and radiographic examination showed a circumscribed unilocular, radiolucent lesion in the left maxillary. After clinical, radiographic and histopathological examinations, an orthokeratinized odontogenic cyst was diagnosed. Surgical treatment was performed with satisfactory results and there have been no clinical or radiographic signs of recurrence to date.

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