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Coordinación General de Investigación de la Facultad de Salud Pública y Nutrición y la Dirección General de Sistemas e Informática de la Universidad Autónoma de Nuevo León

2017, Number 2

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Rev Salud Publica Nutr 2017; 16 (2)

Obesidad y salud, ¿en realidad existe el paciente obeso metabólicamente sano?

Acebo MML

Language: Spanish
References: 57
Page: 44-45
PDF size: 227.27 Kb.


ABSTRACT

Introduction: Obesity is a chronic and multifactorial disease that in recent years has reached levels to be considered as a pandemic. There is ample evidence that the obesity is an important risk factor for developing cardiovascular diseases, which are the leading cause of death worldwide. However, it has been reported that some patients with obesity seem to be protected from metabolic abnormalities because they don't have any of the aforementioned complications, which have been classified as metabolically healthy obesity, although this concept is still controversial. Objective: describe the pathophysiology of obesity to analyze the phenotype of the metabolically healthy obese through literature review. Methods: Study with descriptive review design, the sample material were articles that addressed the description of pathophysiological factors of obesity, the search focused on retrievable items on the platforms PubMed (Medline) and Ebsco through the use of statements “Pathophysiology and Obesity” y “Healthy and Obesity”. Results: To present obesity represents a cardiovascular risk situation on its own, especially the so-called central obesity in promoting the development of cardiovascular risk factors. The metabolically healthy phenotype can reach up to 30% in patients who are obese, which in some cases may delay the start of nutritional treatment because there are no metabolic complications and as the degree of obesity increases or age increases, such complications may develop. Conclusions: Further studies are required in which participants are assessed longitudinally to know the evolution of the phenotype or the response to nutritional interventions and corroborate whether the healthy obese would be an initial stage towards the evolution to the state of pathological obesity.


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