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2015, Number 2

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Rev Educ Bioquimica 2015; 34 (2)

Folatos: su síntesis, metabolismo, transporte y papel en el desarrollo de plantas

Reyes-Hernández BJ, Díaz GRI, Dubrovsky JG

Language: Spanish
References: 51
Page: 39-48
PDF size: 758.93 Kb.


ABSTRACT

Tetrahydrofolate (THF) and its derivatives (5-formyl-THF, 10-formyl-THF, 5-methyl- THF, 5,10-methylene-THF, 5,10-methenyl-THF) are collectively called folates or vitamin B9. Folate deficiency in plants and other organisms causes severe alterations in their development. Animals cannot synthesize folates de novo and plants are the main source of them. Folates donate or accept carbon units for the synthesis of purines, thymidilate, methionine, pantothenate and formyl-methionyl-tRNA, and participate in serine-glycine interconversion and histidine catabolism. Folates, participating in the synthesis of these metabolites compose a complex network, known as one-carbon metabolism. These metabolic aspects and the role of folates in plant development are reviewed in this paper.


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