Anido EVM, Roque GR, Brizuela QR, Amable DT, Pérez BL, Díaz DZ, García-Menocal HJL, Morera PM

Language: Spanish
References: 23
Page: 10-18
PDF size: 118.71 Kb.

ABSTRACT

Introduction: Achalasia is a primary esophageal motor disease with lower esophageal sphincter impairment and esophageal aperistalsis. Its etiology is unknown.
Objective: To observe the epidemiological behavior and characteristic of achalasia patients treated at the National Center for Minimal Invasive Surgery.
Methods: A retrospective, descriptive and observational study was performed with achalasia patients, diagnosed through conventional esophageal manometry and treated at the National Center for Minimal Invasive Surgery from January 2006 to December 2015.
Results: 332 patients were diagnosed with achalasia through manometry. The disease was more frequent in women at the forth decade of life, with more than 4 years of natural history, and without any association to other diseases. The esophageal manometry registered the poor relaxation of the lower esophageal sphincter and no peristalsis.
Conclusions: The disease typical features were identified, on being important the dysphagia patient's clinical follow-up in order to have a final diagnosis of the disease.

REFERENCES

1. O'Neill OM, Johnston BT, Coleman HG. Achalasia: a review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol. 2013 Sep 21;19(35):5806-12.

2. von Rahden BH, Filser J, Seyfried F, Veldhoen S, Reimer S, Germer CT. [Diagnostics and therapy of achalasia]. Chirurg. 2014 Dec;85(12):1055-63.

3. Yasawy MI. Diagnosis and treatment of achalasia patients: a ten-year review of the clinical features. Hepatogastroenterology. 2014 Sep;61(134):1611-6.

4. Boeckxstaens GE, Zaninotto G, Richter JE. Achalasia. Lancet. 2014 Jan 4;383(9911):83-93.

5. Moonen A, Boeckxstaens G. Current diagnosis and management of achalasia. J Clin Gastroenterol. 2014 Jul;48(6):484-90.

6. Muller M. Impact of high-resolution manometry on achalasia diagnosis and treatment. Ann Gastroenterol. 2015 Jan-Mar;28(1):3-9.

7. Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, et al. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015 Feb;27(2):160-74.

8. Pandolfino JE, Kwiatek MA, Nealis T, Bulsiewicz W, Post J, Kahrilas PJ. Achalasia: a new clinically relevant classification by high-resolution manometry. Gastroenterology. 2008 Nov;135(5):1526-33.

9. Zurita Macias Valadez LC, Pescarus R, Hsieh T, Wasserman L, Apriasz I, Hong D, et al. Laparoscopic limited Heller myotomy without anti-reflux procedure does not induce significant long-term gastroesophageal reflux. Surg Endosc [Internet]. 2015 [cited 2016 Sep 15]; 29(6):14628 p. Available from: http://dx.doi.org/10.1007/s00464-014-3824-z.

10. von Rahden BH, Filser J, Reimer S, Inoue H, Germer CT. [Peroral endoscopic myotomy for treatment of achalasia. Literature review and own initial experience]. Chirurg. 2014 May;85(5):420-32.

11. Mikaeli J, Bishehsari F, Montazeri G, Yaghoobi M, Malekzadeh R. Pneumatic balloon dilatation in achalasia: a prospective comparison of safety and efficacy with different balloon diameters. Aliment Pharmacol Ther. 2004;20:431-6.

12. Dughera L, Battaglia E, Maggio D, Cassolino P, Mioli PR, Morelli A, et al. Botulinum toxin treatment of oesophageal achalasia in the old and oldest old: a 1- year follow-up study. Drugs Aging. 2005;22:779-83.

13. Zeng Y, Dai YM, Wan XJ. Clinical remission following endoscopic placement of retrievable, fully covered metal stents in patients with esophageal achalasia. Dis Esophagus. 2014 Feb-Mar;27(2):103-8.

14. Naranjo Hernández D, García Freyre I, Fernández Zulueta A, Verdecia Fernández F, Anido Escobar V, Pascau Illas B. Valoración manométrica del esófago de pacientes operados de acalasia mediante cirugía laparoscópica. Rev Cubana Cir [Internet]. 2008 Dic [citado 2016 Sep 15]; 47(3). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034- 74932008000300004&lng=es.

15. Gray RT, Coleman HG, Lau KW, McCaughey C, Coyle PV, Murray LJ, et al. Heller´s myotomy and pneumatic dilatation in the treatment of achalasia: population-based case-control study assessing long-term quality of life. Dis Esophagus [Internet]. 2015 [cited 2016 Sep 15]. Available from: http://dx.doi.org/10.1111/dote.12445.

16. Sadowski DC, Ackah F, Jiang B, Svenson LW. Achalasia: incidence, prevalence and survival. A population-based study. Neurogastroenterol Motil. 2010;22:e256- 61. doi: 10.1111/j.1365-2982.2010.01511.x.

17. Eunkyung Kim, Hongsub Lee, Hye-kyung Jung and Kwang Jae Lee. Achalasia in Korea: An epidemiologic study using a national healthcare database. J Korean Med Sci.2014;29:576-80.

18. Pohl D, Tutuian R. Achalasia: an overview of diagnosis and treatment. J Gastrointestin Liver Dis. 2007 September;16(3):297-303.

19. Becker J, Niebisch S, Ricchiuto A, Schaic EJ, Lehmann G, Waltgenbach T, et al. Comprehensive epidemiological and genotype-phenotype analyses in a large European sample with idiopathic achalasia. Eur J Gastroenterol Hepatol. 2016 Jun;28(6):689-95.

20. Im SK, Yeo M, Lee KJ. Proteomic identification of proteins suggestive of inmune-mediated response or neuronal degeneration in serum of achalasia patients. Gut Liver. 2013;7:411-6.

21. Coleman HG, Gray RT, Lau KW, McCaughey C, Coyle PV, Murray LJ, et al. Socioeconomic status and lifestyle factors are associated with achalasia risk: a populationbased case-control study. W J Gastroenterol. 2016 april 21;22(5):4002-8.

22. Pandolfino JEA, Gawron AJA. Achalasia: A systematic review. JAMA. 2015;313(18):1841-52.

23. Enestvedt BK, Williams JL, Sonnenberg A. Epidemiology and Practice Patterns of Achalasia in a Large Multi-Center Database. Aliment Pharmacol Ther. 2011;33(11): 1209-14. doi:10.1111/j.1365-2036.2011.04655.x.