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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2005, Number 2

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Rev Biomed 2005; 16 (2)

Adenoviruses: Opportunist pathogens in HIV infection?

González-Muñoz G

Language: Spanish
References: 92
Page: 139-146
PDF size: 50.40 Kb.


ABSTRACT

The gastrointestinal tract (GI) is one of the organs frequently affected in the patients with Human Immunodeficiency Virus (HIV), and the Acquired Immunodeficiency Syndrome (AIDS), in such a way that deteriorations or pathologies in this tract represent an important cause for morbidity and mortality. Where ever the deterioration is located from the pharynx to the rectum the cardinal sign, due to its frequency and clinical significance is diarrhea, which is present in 55 to 93% of all cases, at some stage of the disease. This manifestation is a sign of a wide range of infectious diseases, neoplasic, or of other etiology, which affects the GI tract at any level in patients with HIV infection. Virus are found among the infectious agents, however in many cases it is not possible to determine the implication of any viral agent, partly due to the exclusion in routine diagnostic procedures in test to detect pathogenic enteric, such as the adenovirus, whose important potential and possible role as an opportunist infection in AIDS, has been minimized on occasions. Despite the numerous reports reflecting the importance of the study of the mechanisms in which strains of adenovirus, are found colonizing the GI tract of patients with AIDS, the significance of this virus in the pathogen has no been clarified, because these mechanisms have not been properly studied.


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