Castillo-Luna R, Delgado-Amador DE, Arteaga-Gómez AC

Language: Spanish
References: 0
Page: 224-233
PDF size: 138.31 Kb.

ABSTRACT

Background: The incidence of ovarian cancer diagnosed during pregnancy is 1: 10,000-100,000 pregnant women. Surgery and use of chemotherapy during pregnancy is feasible after the first trimester. The management of this patients should be performed by a multidisciplinary team.
Objetive: To describe the treatment and perinatal outcomes of patients diagnosed with ovarian cancer during pregnancy.
Material and Methods: Retrospective, observational and descriptive study included 5 patients with ovarian cancer associated with pregnancy treated at the Instituto Nacional de Perinatología Isidro Espinosa de los Reyes of 2009-2014. Demographic data, gynecological findings, symptoms, weeks of gestation at the time of diagnosis of malignancy, histological type and staging of neoplasia (FIGO 2014) were obtained from the clinical file. The results were expressed in measures of central tendency.
Results: The mean age of patients was 24.6 ± 8.9 years. All were performed conservative surgery during pregnancy (median 22.8 ± 6.4 weeks) without observing complications related to this. Three patients were in stage I, 1 in IIIA2 an 1 in IVB. 4 newborn and healthy, gestational age 38 ± 1.1 weeks, weight of 2,845 ± 700 g neonates were obtained. The evolution and post-natal hospital stay was satisfactory.
Conclusion: The diagnosis, treatment and monitoring of ovarian cancer during pregnancy should be done in a multidisciplinary manner, considering the stage of the disease, gestational age and patient decision of the patient, in order to offer the best alternatives. It requires studies of long term follow up of children exposed to chemotherapy during pregnancy to evaluate the effects of it during development.