medigraphic.com
ISSN 0016-3813 (Print)

2002, Number 2

<< Back Next >>

Gac Med Mex 2002; 138 (2)

Alleles of the Major Histocompatibility Complex Related with the Susceptibility to the Development of Takayasu Arteritis.

Flores-Domínguez C, Hernández-Pacheco G, Zúñiga J, Gamboa R, Granados J, Reyes PA, Vargas-Alarcón G

Language: Spanish
References: 71
Page: 177-184
PDF size: 74.35 Kb.


ABSTRACT

Objective: Since 1972, the relationship between HLA alleles and the susceptibility for Takayasu arteritis (TA) has been studied on different populations. Hence the results up to date are heterogeneous, the objective of the present review is to analyze the relationship between the presence of HLA alleles and the susceptibility for the development of TA considering the ethnic origin of the studied populations. Material and methods: We carried out a bibliographic review from clinical articles of case and controls studies on different populations on which the relationship between HLA alleles and the susceptibility for TA was studied, published since 1972 until February 2000. Results: We reviewed articles of studies on Asian, Arab, North-American and Mexican Mestizo populations. On Asian populations TA was associated with HLA-A31, -B52, -B39,-B5 and -DR2, on Arabs with HLA-A2, -A9, -B35 and -DR7, on North-Americans with HLA-DR4 and on Mexican Mestizo with HLA-B5, -B52 and -DR6. On the other hand, recent reports establish that several HLA-B alleles (HLA-B52 and HLA-B39) associated with the disease share some residues important on the antigen presentation. Conclusions: Hence the heterogeneity of the results obtained up to date, it stands out the increase on HLA-B52 and HLA-DR4 reported on ethnically different populations. More recent data point the possible participation of an epitope located on the peptide-binding site of the HLA-B molecule (positions 63 and 67) that seems to be shared by several alleles associated with the disease. These residues might be participating on the presentation of an unknown antigen that would unchain the disease on the genetically susceptible individuals group.


REFERENCES

  1. 1. Rizzi R. Takayasu's arteritis: a cell-mediated large-vessel vasculitis. Int J Clin Lab Res 1999;29:8-14.

  2. 2. Numano F, Kakuta T. Takayasu arteritis- five doctors in the history of Takayas'u arteritis. Int J Cardiol 1996;54 (Suppl):S1-S10.

  3. 3. Sekiguchi M, Suzuki J. An overview on Takayasu arteritis. Heart Vessels 1998;(Suppl 7):6-10.

  4. 4. Puig-Solanes M, Quiroz J. El cuadro ocular de los síndro-mes del arco aórtico. Ann Soc Mex Oftal 1957;30:26-33.

  5. 5. Sánchez-Torres G. Avances en el conocimiento de la arteritis de Takayasu. Arch Inst Cardiol Mex 1997;67:263-267.

  6. 6. Desiron Q, Zeaiter R. Takayasu arteritis. Acta Chir Belg 2000;100:1-16.

  7. 7. Robles M, Reyes PA. Takayasus arteritis in Mexico: a clinical review of 44 consecutive cases. Clini Exp Rheum 1994;12:381-388.

  8. 8. Martínez-Baños, Dábague J, Reyes PA. Arteritis de Takayasu en México. Una serie de 65 casos consecutivos. Rev Mex Reumatol 1999;14:121-127.

  9. 9. Dábague J, Reyes PA. Takayasu arteritis in Mexico: a 38-year clinical perspective through literature. Int J Cardiol 1996;(Suppl 54):5103-S109.

  10. Numano F, Kobayashi Y. Takayasu arteritis- beyond pulselessness. Intern Med 1999;38:226-232.

  11. Hotehi M. Pathological studies on Takayasu arteritis. Heart Vessels 1992;(Suppl 7):11-17.

  12. Sharma BK, Jain S, Suri S, Numano F. Diagnostic criteria for Takayasu arteritis. Int J Cardiol 1996;(Suppl. 54):S141-SI47.

  13. Sharma BK. Systemic manifestations of Takayasu arteritis: the expanding spectrum. Int J Cardiol 1996;54(Suppl):S149-S154.

  14. Matsunaga N, Hayashi K, Sakamoto I, Ogawa Y, Matsumoto T. Takayasu arteritis Radiographics 1997;17:579-594.

  15. Arend WP, Beat AM, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of Takayasu arteritis. Arthritis Rheum 1990;33:1129-1134.

  16. Hata A, Makoto N, Ryutaro M, Numano F. Angiographic findings of Takayasu arteritis new classification. Int J Cardiol 1996;54(Suppl:)S155-S163.

  17. Choe YH. Takayasu arteritis diagnosis with MR imaging and MR angiography in acute and chronic active stages. J Magn Reson Imagin 1999;10:751-757.

  18. Raninen RO, Kupari MM, Pamilo MS, et al. Ultrasonography in the quantification of arterias involvement in Takayasu's arteritis. Scand J Rheumatol 2000;29:56-61.

  19. Meneghetti MI, Vazquez J, Alvarado D, Conde M, Sánchez-Torres G. Takayasu arteritis usefulness of radiologic and anziograghic studies. Arch Inst Cardiol Mex 1984;59:405-414.

  20. Lande A, Rossi P. The value of total aortography in the diagnosis of Takayasu´s arteritis. Radiology 1975;114:287-297.

  21. Buckley A, Southwood T, Culham G, Nadel H, Malleson P, Petty R. The role of ultrasound in evaluation of Takayasu arteritis. J Rheumatol 1991;18:1073-1080.

  22. Choe YH, Lee WR. Magnetic resonance imaging diagnosis of Takayasu arteritis. Int JCardiol 1998;66(Suppl 1); S175-SI79.

  23. Del Corso L, Moruzzo D, Agelli M, Pentimone F. Takayasu's arteritis in steroid therapy. Seven years follow-up. Pamminerva Med 1999;41:355-358.

  24. lwao I. Medical treatment of Takayasu arteritis. Heart Vessels 1992;Suppl 7:S133-S137.

  25. Park JH, Han MC, Kim SH, Oh BH, Park YB, Seo JD. Takayasu arteritis: angiographic findings and results of angiopiglu. AJR Am J Roentgenol 1989;153:1069-1074.

  26. Cotch MF. The socioeconomic impact of vasculitis. Curr Opin Rheumatol 2000;12:20-23.

  27. Sato EI, Hatta FS, Levy-Neto M, Fernandes S. Demographic, clinical, and angiographic data on patients with Takayasu arteritis iu Brazil. Int J Cardiol 1998;66(Suppl 1): S67-S70.

  28. Cañas A, Jimenez C, Ramírez L, et al. Takayasu arteritis in Colombia. Int J Cardiol 1998;66(Suppl 1):S73-S79.

  29. Sagar S, Ganguly NK, Morris Koicha, Sharma BK. immunopathogenesis of Takayasu arteritis. Heart Vessels 1992;(Suppl 7):85-90.

  30. Campbell RD, Trowsdale J. Map of the human MIHC. Immunol Today 1993;14:349-352.

  31. Dunham Y, Sargent CA, Trowsdale J, Cambell RD. Molecular mapping of the human major histocompatibility complex by pulsed-field gel electrophoresis. Proc Natl Acad Sci USA 1987;84:7232-7241.

  32. Trowsdale J. Genetic and polymorphism class II antigens. Br Med Bull 1987;43:15-36.

  33. Sargent CA, Dunham Y, Trowsdale J, Campbell RD. Human major histocompatibility complex contains genes for the major heat shock protein HSP70. Proc Natl Acad Sci USA 1989;86:1968-1970.

  34. Alper CA, Awdeh ZL, Raum DD, Yunis EJ. Extended major histocompatibility complex haplotypes in man: role of alleles analogous to murine t mutants. Clin Immunol Immunopathol 1982;24:276-85.

  35. Bodmer JG, Marsh SGE, Albert ED, et al. Nomenclature for factors of the HLA system 1998. Tissue Antigens 1999;53:407-446.

  36. Alper CA. Inherited structural polymorphism in human C2: evidence for genetic linkage between C2 and Bf. J Exp Med 1976;144:1111-1115.

  37. Awdeh ZL, Raum D, Alper CA. Genetic polymorphism of the fourth component of human complement: detection of heterozygotes. Nature 1979;282:205-207.

  38. Awdeh ZL, Alper CA. Inherited structural polymorphism of the fourth component of human complement (C4). Proc Natl Acad Sci USA 1980;77:3576-3580.

  39. Aper CA, Raum D, Karp S, et al. Serum complement "supergens" of the major histocompatibility complex in man (complotypes). Vox Sang 1983;42:62-67.

  40. Imanashi T, Akaza T, Kimura A, Tokunaga K, Gojobori T. Allelle and haplotype frequencies for HLA and complement loci in various ethnic groups. In: Tsuji K, Aizawa M, Sasazuki T. HLA 1991. Proceeding of Eleventh International Histocompatibility Workshop and Conference. Vol 1. Oxford UK: Oxford University Press; 1992. p.1065-1220.

  41. Weckman AL, Vargas Alarcón G, López M, et al. Frequencies of HLA-A and HLA-B alleles in a Mexico City mestizo sample. Am J Hum Biol 1997;9:1-5.

  42. De Leo C, Castelán N, López M, et al. HLA class I and class II alleles and haplotypes in Mexican Mestizos established from serological typing of 50 families. Hum Biology 1997;69:809-818.

  43. Bodmer JG, Kennedy LJ, Lindsay J et al. Applications of serology and the ethnic distribution of three locus HLA haplotypes. Brit Med Bull 1987;43:94-121.

  44. Cavalli-Sforza LL, Bodmer WF. The genetics of human populations. San Francisco, CA, USA: Freeman. 1971. p. 943.

  45. Degos L, Dausset J. Human migrations and linkage dise-quilibrium of HLA system. Immunogenetics 1974;1:195-210.

  46. Tiwari J, Terasaki P. HLA and disease associations. New York: Springer-Verlang; 1985.

  47. Matsushita S, Fujisao S, Nishimura Y. Molecular mechanisms underlying HLA-DR-associated susceptibility to autoimmunity. Int J Cardiol 1996;54 (Suppl):S81-S90.

  48. Kimura A, Kitamura H, Date Y, Numano F. Comprehensive analysis of HLA genes in Takayasu arteritis in Japan. Int J Cardiol 1996;54(Suppl):S61-S69.

  49. Numano F, Kobayashi Y, Maruyama Y, Kakyta T, Miyata T, Kishi Y. Takayasu arteritis: clínical characteristics and the role of genetic factors in its pathogenesis. Vasc Med 1996;1:227-233.

  50. Kitamura H, Kobayashi Y, Kimura A, Numano F. Association of clinical manifestations with HLA-B alleles in Takayasu arteritis. Int J Cardiol 1998;66(Suppl 1):S121-S126.

  51. lohisa I, Numano F, Maezawa H, Sasazuki T. HLA-Bw52 in Takayasu disease. Tissue Antigens 1978;12:246-248.

  52. Numano F. Hereditary factors of Takayasu arteritis. Heart Vesseis 1992;(7 Suppl):68-72.

  53. Charoenwongse P, Kangwanshiratada O, Boonman R, Hoomsindhu U. The association between HLA antigens and Takayasus arteritis in Thai patients. Int J Cardiol 1998;(Suppl 1):S117-S120.

  54. Hee-Park M, Bae-Park Y. IHLA typing of Takayasu arteritis in Korea. Heart Vessels 1992;7(Suppl):81-84.

  55. Nishimura Y. HLA-linked susceptibility to intractable vasculitis syndrome. Nippon Rishno 1994;52:2000-2005.

  56. Nishimura Y. Molecular analysis of HLA class II-associated susceptibility to subtypes of autoimmune diseases unique to Asians. Int J Cardiol 1998;66(Suppl 1):S93-S104.

  57. Mahra NK, Jaini R, Balamurugan AS, et al. Immunogenetic analysis of Takayasu arteritis in Indian patients. Int J Cardiol 1998;(Suppl 1):S127-S132.

  58. Castro G, Chavez-Peón F, Sánchez-Torres G, Reyes PA. HLA-A and B antigens in Takayasu arteritis. Rev Invest Clin 1982;34:15-17.

  59. Sattar MA, White AG, Eklof B, Fenech FF. Takayasu's disease in Arabs. Postgrad Med 1985;61:387-390.

  60. Yajima M, Numano F, Park YB, Sagar S. Comparative studies of patients with Takayasu arteritis in Japan, Korea and India comparison of clinical manifestations, angiography and HLA-B antigen. Jpn Circ J 1994;58:9-14.

  61. Volkman DJ, Mann DL, Fauci AS. Association between Takayasu's arteritis and B cell alloanticen in North Americans. N Engl J Med 1982;306:464-465.

  62. Kharaishi MM, Gladman DD, Gagenais P, et al. HLA antigens in North American patients with Takayasu arteritis. Arthritis Rheum 1992;35:573-575.

  63. Lisker R, Ramírez E, Pérez-Briceño R, Granados J, Babinsky V. Gene frequencies and admixture estimates in four Mexican Urban Centers. Hum Biol 1990;62:791-801.

  64. Girona E, Yamamoto-Furusho J, Cutiño T, et al. HLA-DR6 (possibly DRBI*1301) is associated with susceptibilily to Takayasu arteritis in Mexicans. Heart Vessels 1996;11:277-280.

  65. Yoshida M, Kimura T, Katsuragi K, Numano F, Sasazuki T. DNA tying of HLA-B gene in Takayasu's arteritis. Tissue Antigens 1993:42:87-90.

  66. Vargas-Alarcón G, Zuñiga J, Gamboa R, Hernández-Pacheco G, Hesiquio R, Cruz D, Martínez-Baños D, Portal-Celhay C, Granados J, Reyes P. DNA sequencing of HLA-B alleles in Mexican patients with Takayasu arteritis. Int J Cardiol 2000;75:117-122.

  67. Numano F. Differences in clinical presentation and outcome in different countries for Takayasu arteritis. Curr Opin Rheumatol 1997;9:12-15.

  68. Numano F, Isohisa J, Kishi Y, et al. Takayasu's disease in twin sisters. Circulation 1978;58:173-77.

  69. Isohisha I, Numano F, Nakajo Y, et al. Two sisters with Takayasu disease who have grown separately in different environments. Nippon Naika Gakkai Zasshi 1984;73:1342-1346.

  70. Tyagi S, Reddy NK, Khalilullah M. Familial occurrence of non-specific aortoarteritis in two sisters. Indian Heart J 1991;43:193-194.

  71. Makino N, Senda Y, Yamaguchi Y. Takayasu's disease in two brothers. Analysis of HLA types. Br Heart J 1981;46:446-448.




2020     |     www.medigraphic.com