2017, Number 4
<< Back Next >>
Rev Fac Med UNAM 2017; 60 (4)
Thyroid storm, an endocrine emergency. Case report and literature review
Mercado CE, García CCF, Arellano TA, Rodríguez HA
Language: Spanish
References: 12
Page: 27-36
PDF size: 286.93 Kb.
ABSTRACT
The thyroid storm is a critical and rare disease, which conditions
the dysfunction of multiple organs due to the excessive
effect of thyroid hormones. This endocrine dysfunction has
a high mortality and generates typical manifestations such
as tachycardia, fever, gastrointestinal alterations, and cardiovascular
and neurological disorders.
The diagnosis is primarily clinical and can be supported by
the scale of “Burch and Wartofsky”. Serum concentrations of
thyroid hormones are not correlated with the severity of the
symptoms, but their assessment is useful to confirm the diag
nosis. Other tests that may help complement the diagnosis
are thyroid ultrasound, cardiac markers, and assessment of
liver and kidney function.
It is usually possible to identify a triggering factor, although
in exceptional cases, the thyroid storm may also be the initial
manifestation of some thyroid pathology.
Therapeutic strategies are aimed at inhibiting the synthesis
and the release of thyroid hormones as well as reducing their
concentration and peripheral effects, without forgetting the
treatment of the triggering factor.
REFERENCES
Franklyn JA, Boelaert K. yrotoxicosis. Lancet. 2012; 379(9821):1155-66.
Devereaux D, Tewelde SZ. Hyperthyroidism and yrotoxicosis. Emerg Med Clin North Am [Internet]. Elsevier Inc; 2014;32(2):277-92. [Citado: 31 de marzo de 2017]. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/ 24766932%0Ahttp://linkinghub.elsevier.com/retrieve/pii/ S0733862713001314
Papi G, Corsello SM, Pontecorvi A. Clinical concepts on thyroid emergencies. Front Endocrinol (Lausanne). 2014; 5(jul):1-11.
De Leo S, Lee SY, Braverman LE. Hyperthyroidism. 2016; 288:906-18.
Klubo-Gwiezdzinska J, Wartofsky L. yroid Emergencies. Med Clin NA. 2012;96:385-403.
Burch H, Wartofsky L. Life-threatening thyrotoxicosis. yroid storm. Endocrinol Metab Clin North Am. 1993; 22(2):263-77.
Satoh T, Isozaki O, Suzuki A, Wakino S, Iburi T, Tsuboi K, et al. 2016 Guidelines for the management of thyroid storm from e Japan yroid Association and Japan Endocrine Society (First edition). Endocr J [Internet]. 2016;84(6):912-
[Citado: 31 de marzo de 2017]. Disponible en: http:// www.ncbi.nlm.nih.gov/pubmed/27746415 8. Akamizu T, Satoh T, Isozaki O, Suzuki A, Wakino S, Iburi T, et al. Diagnostic Criteria, Clinical Features, and Incidence of yroid Storm Based on Nationwide Surveys. yroid. 2012;22(7):661-79.
Mills L, Lim S. Identifying And Treating yroid Storm And Myxedema Coma In e Emergency. Emerg Med Pract. 2009;11(8):1-26.
Mantilla D, Echin ML, Perel C. Hipertiroidismo y sistema cardiovascular. Bases fisiopatológicas y su manifestación clínica. Insufic Card. 2010;5(4):157-77.
Surawicz B, Knilans T. Chou’s Electrocardiography in Clinical Practice. 6th Edition. Philadelphia, EUA: Saunders Elsevier Inc., editor. 2008. 752 p.
Cooper D. Antithyroid drugs. N Engl J Med. 2005;352(21): 905-17.