2016, Number 09
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Ginecol Obstet Mex 2016; 84 (09)
Pneumomediastinum associated with hyperemesis gravidarum: a case report
Germes-Piña F, Flores-Franco RA, Acosta-Orozco DM, Verdugo-Castro CPN
Language: Spanish
References: 33
Page: 586-592
PDF size: 546.68 Kb.
ABSTRACT
Background: The hyperemesis gravidarum is a severe illness of
nauseas and vomit that is present in the first trimester of the pregnancy,
it has an incidence of 0.3 to 2%, it has been associated to weight loss,
electrolytic disturbances, ketonuria, dehydration and in very seldom
cases spontaneous pneumomediastinum.
Clinic case: A 21 years old female patient, primigest, in the first
trimester of gestation, she started her disease with nauseas and vomiting
more than 15 times during 6 hours period, odynophagia, dysphonia
and pain in the cervical region, loss of 5 kilograms in the last month.
The physical examination showed the patient in bad conditions, dehydration,
neck with volume increased and emphysema subcutaneus,
crakles until torax. Laboratory findings with hypokalemia, leukocytosis,
acute kidney failure, and elevation of hepatic enzymes. The initial
treatment was with intravenous fluids resuscitation, hydroelectrolytic
balance restoration, antiemetic treatment and rest, it was taken TC of
neck and torax, and was exclude any laryngeal and esophageal injury
and perforation, but it showed air in the mediastinum. Conservative
management with favorable evolution and completed resolution in
7 days.
Conclusion: It is very important that the medical doctor must keep
in mind the different diagnosis of and take an opportune decision in
case of present those complications potentially fatal to the mother.
REFERENCES
Niemeijer MN, Grooten IJ, Vos N, et al. Diagnostic markers for hyperemesis gravidarum: a systematic review and metaanalysis. Am J Obstet Gynecol 2014;211:150.e1-15.
Sonkusare S. Hyperemesis gravidarum: a review. Med J Malaysia 2008 Aug;63(3):272-6.
Kosku NK, Koyuncu F. Hyperemesis gravidarum: current concepts and management. Postgrad Med J 2002;78:76-79.
Refuerzo JS, Smith JA, Ramin SM. Clinical features and evaluation of nausea and vomiting of pregnancy [en línea]. Dirección URL: .
Buckwalter JG, Simpson SW. Psychological factors in the etiology and treatment of severe nausea and vomiting in pregnancy. Am J Obstet Gynecol 2002;186:S210.
Macklin CC. Transport of air along sheaths of pulmonic blood vessels from alveoli to mediastinum: clinical implications. Arch Intern Med 1939;64:913-926.
Sakai M, Murayama S, Gibo M, et al. Frequent cause of the Macklin effect in spontaneous pneumomediastinum: demonstration by multidetector-row computed tomography. J Comput Assist Tomogr 2006;30:92-94.
Flores-Franco RA, Limas-Frescas NE. The overused airway: lessons from a young trumpet player. Med Probl Perform Art 2010;25:35-38.
Manco JC, Terra-Filho J, Silva GA. Pneumomediastinum, pneumothorax, and subcutaneous emphysema following the measurement of maximal expiratory pressure in a normal subjet. Chest 1990;98:1530-1532.
Takada K, Matsumoto S, Hiramatsu T, et al. Spontaneous pneumomediastinum: an algoritm for diagnosis and management. Ther Adv Respir Dis 2009;3:301-307.
Karson EM, Saltzman D, Davis MR. Pneumomediastinum in pregnancy: two case reports and a review of the literature, pathophysiology, and management. Obstet Gynecol 1984;64:39S-43S.
Jayran-Nejad Y. Subcutaneous emphysema in labour. Anesthesia 1993;48:139-140.
Hatzitolios AI, Ntaios G, Sion ML. Both spontaneous pneumothorax and spontaneous pneumomediastinum may constitute a complication in underweight patients. Chest 2008;134:216-217.
Hochlehnert A, Löwe B, Bludau HB, et al. Spontaneous pneumodiastinum in anorexia nervosa: a case report and review of the literature on pneumomediastinum and pneumothorax. Eur Eat Disorders Rev 2010;18:107-115.
Sahebjami H, Vassallo CL, Wirman JA. Lung mechanics and ultrastructure in prolonged starvation. Am Rev Resp Dis 1978;117:77-83.
Cook VJ, Coxson HO, Mason AG, et al. Bronchiectasis and nutritional emphysema in severe anorexia nervosa. Can Resp J 2001;8:361-365.
Coxson HO, Chan IHT, Mayo JR, et al. Early emphysema in patients with anorexia nervosa. Am J RespCrit Care Med 2004;170:748-752.
Karson EM, Saltzman D, Davis MR. Pneumomediastinum in pregnancy: two case reports and a review of the literature, pathophysiology, and management. Obstet Gynecol 1984;64:39S-43S.
Chatfield WR, Bowditch JD, Forrest CA. Spontaneous pneumomediastinum complicating anorexia nervosa. Br Med J 1979;1(6156):200-201.
Woolford TJ, Birzgaliz AR, Lundell C, Farrington WT. Vomiting in pregnancy resulting in oesophageal perforation in a 15-year-old. J Laryngol Otol 1993;107:1059-1060.
Schwartz M, Rossoff L. Pneumomediastinum and bilateral pneumothoraces in a patient with hyperemesis gravidarum. Chest 1994;106:1904-1906.
Gorbach JS, Counselman FL, Mendelson MH. Spontaneous pneumomediastinum secondary to hyperemesis gravidarum. J Emerg Med 1997;5:639-643.
Yamamoto T, Suzuki Y, Kojima K, et al. Pneumomediastinum secondary to hyperemesis gravidarum during early pregnancy. Acta Obstet Gynecol Scand 2001;80:1143-1145.
Guang LS, Fumiko O, Akiko S, et al. Pneumomediastinum following oesophageal rupture associated with hyperemesis gravidarum. J Obst Gynaecol Res 2002;28:172-175.
Sivanesan K, Tirney J. Pneumomediastinum associated with hyperemesis gravidarum. Scott Med J 2007;52:55.
Khiyar Y, Armstrong R, Penston JG. Hyperemesis gravidarum: two unusual complications occurring in the same patient [en línea]. Dirección URL: .
Iyer VN, Joshi AY, Ryu JH. Spontaneous pneumomediastinum: analysis of 62 consecutive adult patients. Mayo Clin Proc 2009;84:417-421.
Okada M, Adachi H, Shibuya Y, et al. Diagnosis and treatment of patients with spontaneous pneumomediastinum. Resp Invest 2014;52:36-40.
Caceres M, Ali SZ, Braud R, et al. Spontaneous pneumomediastinum: a comparative study and review of the literatura. Ann Thorac Surg 2008;86:962-966.
Macia I, Moya J, Ramos R, et al. Spontaneous pneumomediastinum: 41 cases. Eur J Cardiothor Surg 2007;31:1110-1114.
Bouhuys A. Physiology and musical instruments. Nature 1969;221:1199-1204.
Forshaw MJ, Khan AZ, Strauss DC, et al. Vomiting-induced pneumomediastinum and subcutaneous emphysema does not always indicate Boerhaave’s syndrome: report of six cases. Surg Today 2007; 37:888-892.
Brent R. The pulmonologist’s role in caring for pregnant women with regard to the reproductive risks of diagnostic radiological studies or radiation therapy. Clin Chest Med 2011;32:33-42.