Rosero ACP, Castillo SGK, Jácome CAP

Language: Spanish
References: 19
Page: 55-58
PDF size: 294.18 Kb.

ABSTRACT

Reticulohistiocytosis were described in 1982 by Goette et al, who referred three related clinical pictures: reticulohistiocytoma skin alone (characterized by a single cutaneous lesion, usually in the head or neck), multicentric reticulohistiocytosis (RHM; with multiple, arthritis, skin lesions and sometimes other internal manifestations), and diffuse cutaneous reticulohistiocytosis (papular rash on the face, trunk and extremities that forms plaques, with no evidence of joint or systemic disease). The disease is characterized by destructive and mutilating arthritis, nail changes, lymphadenopathy, visceral lymphocytic infiltration associated with papulonodular skin lesions due to a proliferation of histiocytes and giant cells. The RHM progresses to mutilating arthritis in 45% of the cases, compared with 5% for rheumatoid and psoriatic arthritis. We report a new case of multicentric reticulohistiocytosis in Ecuador and we review the literature.

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