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ISSN 1561-3046 (Electronic)

2016, Number 2

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Rev Cub Med Mil 2016; 45 (2)

Metabolic syndrome as a risk factor for breast cancer. Usefulness of Metformin®

Jova EZ, González SOC, Arpa GÁ

Language: Spanish
References: 52
Page: 195-205
PDF size: 72.23 Kb.


ABSTRACT

Introduction: A review is made on the relation between breast cancer and the metabolic syndrome and the possible usefulness of Metformin® in this disease treatment. Objective: Establish a theoretical framework for future research in this field. Methods: breast cancer is one of the neoplastic diseases with the highest incidence in Cuba and worldwide. Among its risk factors, the metabolic syndrome stands out significantly. Metformin® is a drug of proven utility in the management of metabolic syndrome and diabetes mellitus. Currently, meta-analyzes of retrospective studies on the use of Metformin® as sole therapy or combined with other drugs in diabetic patients with breast cancer are misleading and show increase or no difference in survival. Conclusions: Most studies are not conclusive and more confirmation is recommended.


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