2017, Number 2
<< Back Next >>
Medisur 2017; 15 (2)
Clinical-epidemiological characterization of breast Paget's disease. 37 year study
Torres AL, Puerto LJA, Guerra PE, Caballero AN
Language: Spanish
References: 29
Page: 277-281
PDF size: 162.88 Kb.
ABSTRACT
Foundation: Breast Paget’s disease in is uncommon, representing only 1 to 1.5% of the total breast cancers reported. Some authors consider it a special form of breast cancer and others only an extension of an intraductal carcinoma that reaches the nipple.
Objective: to characterize Breast Paget’s disease from the clinical-epidemiological point of view in operated patients.
Methods: A descriptive study, case A descriptive study, case series type of patients (N = 27) with a diagnosis of Paget’s disease of the breast, operated at the Hospital Provincial de Cienfuegos, from January 1, 1980 to December 31, 2016. For these patients, it was analyzed, sex, age, affected breast, clinical form, presence of underlying tumor, surgical technique applied and survival.
Results: This disease represented only 1.08% of the cancers operated during the study period. It appeared more frequently in the age group of 61-70 years and the clinical form that predominated was ulcerative. The largest number of patients (44.0%) died before five years.
Conclusion: In Cienfuegos Breast Paget’s disease has a low incidence, which coincides with the results of reviewed national and international studies.
REFERENCES
Bas A, Rodríguez T, Arias LC. Enfermedad de Paget de la mama. Presentación de un caso. Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta [revista en Internet]. 2014 [citado 4 May 2016];39(7):[aprox. 10p]. Disponible en: http://www.revzoilomarinello.sld.cu/index.php/zmv/article/view/172/311
Valladares Valle M, Conde Cueto T, Díaz Yánez NM. Enfermedad de Paget, variedad especial de cáncer mamario, presentación de un caso. Medisur [revista en Internet]. 2012 [citado 4 Mar 2016];10(6):[aprox. 8p]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1727-897X2012000600009
Ortiz Hidalgo C, Moreno Collado C. Sir James Paget: La enfermedad de Paget y otras contribuciones a la medicina. Gac Méd Méx [revista en Internet]. 1996 [citado 4 Mar 2016];132(6):[aprox. 12p]. Disponible en: http://www.anmm.org.mx/bgmm/1864_2007/1996-132-6-631-636.pdf
Ozerdem U, Swistel A, Antonio LB, Hoda SA. Invasive Paget disease of the nipple: a brief review of the literature and report of the first case with axillary nodal metastases. Int J Surg Pathol. 2014;22(6):566-9
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N. Mammary and extramammary Paget´s disease. An Bras Dermatol. 2015;90(2):225-31
Sánchez JM, Molinero JA, Ferreres JR, Masferrer E. Enfermedad de Paget extramamaria. SEMERGEN. 2011;37(9):504-7
Ellis H. Sir James Paget: Paget´s disease of the nipple, Paget´s disease of bone. J Perioper Pract. 2013;23(4):91-2
Ishida M, Yoshida K, Kagotani A, Arita N, Iwamoto N, Iwai M, et al. Pigmented paget´s disease: a diagnostic pitfall. Diagn Cytopathol. 2014;42(8):732-3
Negri G, Bulatko AK, Luethy ME, Kasal A, Mazzoleni G, Mian C, et al. Cytoplasmic expression of human papilloma virus L1 capsidic protein in mammary and extramammary Paget disease. Histopathology. 2013;63(1):139-42
Crignis GS, Abreu Ld, Buçard AM, Barcaui CB. Polarized dermoscopy of mammary Paget disease. An Bras Dermatol. 2013;88(2):290-2
Torres L. Enfermedad de Paget de la mama. A propósito de un caso. Finlay [revista en Internet]. 2015 [citado 22 Mar 2017];5(1):[aprox. 3p]. Disponible en: http://www.revfinlay.sld.cu/index.php/finlay/article/view/351/1388
Yerushalmi R, Sulkes A. Paget`s disease and male breast cancer. Isr Med Assoc J. 2015;17(6):396
Leibou L, Herman O, Frand J, Kramer E, Mordechai S. Paget´s disease of the male breast with underlying ductal carcinoma in situ. Isr Med Assoc J. 2015;17(1):64-5
Bansal S, Sahoo B, Agarwal P, Garg VK, Rao S. A rare presentation of mammary Paget´s disease involving the entire breast in the absence of any underlying ductal malignancy. Indian J Dermatol Venereol Leprol. 2013;79(4):518-21
Sanders M, Lester S. Paget disease of the breast with invasion from nipple skin into the dermis. Arch Pathol Lab Med. 2013;137(3):307
Sandoval AC, Drews K, Gómez CR, Yepes MM, Lippman ME. Paget´s disease of the nipple. Breast Cancer Res Treat. 2013;141(1):1-12
Crignis GS, Abreu Ld, Buçard AM, Barcaui CB. Polarized dermoscopy of mammary Paget disease. An Bras Dermatol. 2013;88(2):290-2
Ling H, Hu X, Xu XL, Liu ZB, Shao ZM. Patients with nipple-areola Paget´s disease and underlying invasive breast carcinoma have very poor survival: a matched cohort study. PLoS One. 2013;8(4):e61455
Dominici LS, Lester S, Liao GS, Guo L, Specht M, Smith BL, et al. Current surgical approach to Paget´s disease. Am J Surg. 2012;204(1):18-22
Lohsiriwat V, Martella S, Rietjens M, Botteri E, Rotmensz N, Mastropasqua MG, et al. Paget´s disease as a local recurrence after nipple-sparing mastectomy: clinical presentation, treatment, outcome, and risk factor analysis. Ann Surg Oncol. 2012;19(6):1850-5
Anuario Estadístico de Salud [Internet]. La Habana: MINSAP; 2016 [citado 22 Ene 2017]. Disponible en: http://files.sld.cu/dne/files/2016/04/Anuario_2015_electronico-1.pdf
Torres L, Sarmiento J, Sánchez A, Pacheco O, Capin N, Rojas P. Cáncer de mama. Caracterización durante el decenio 1996-2005. Medisur [revista en Internet]. 2008 [citado 21 Mar 2017];5(3):[aprox. 6p]. Disponible en: http://www.medisur.sld.cu/index.php/medisur/article/view/292
Sanders MA, Dominici L, Denison C, Golshan M, Wiecorek T, Lester SC. Paget disease of the breast with invasion from nipple skin into the dermis: an unusual type of skin invasion not associated with an adverse outcome. Arch Pathol Lab Med. 2013;137(1):72-6
Lee HW, Kim TE, Cho SY, Kim SW, Kil WH, Lee JE, et al. Invasive Paget disease of the breast: 20 years of experience at a single institution. Hum Pathol. 2014;45(12):2480-7
Kiyohara T, Tokuriki A, Kanamori Y, Yasuta M, Imamura Y, Kumakiri M. Superficial sebaceous carcinoma on the areola clinically mimicking mammary Paget´s disease. J Dermatol. 2013;40(2):145-7
Vohra P, Ljung BM, Miller TR, Hwang ES, van Zante A. Paget´s disease of the breast masquerading as squamous cell carcinoma on cytology: a case report. Diagn Cytopathol. 2012;40(11):1015-8
Zheng S, Song QK, Zhao L, Huang R, Sun L, Li J, et al. Characteristics of mammary Paget´s disease in China: a national-wide multicenter retrospective study during 1999-2008. Asian Pac J Cancer Prev. 2012;13(5):1887-93
Duan X, Sneige N, Gullett AE, Prieto VG, Resetkova E, Andino LM, et al. Invasive paget disease of the breast: clinicopathologic study of an underrecognized entity in the breast. Am J Surg Pathol. 2012;36(9):1353-8
Marques JC, Cuzzi T, Carneiro S, Parish LC, Ramos M. Paget´s disease of the breast. SKINmed. 2012;10(3):160-5