2017, Number 1
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RCU 2017; 6 (1)
Use of thymoglobulin and basiliximab in immunosuppression induction therapy in renal transplantation
Leyva TC, Calderón CMA, Pérez RA, Pérez PVJC
Language: Spanish
References: 18
Page: 2-13
PDF size: 293.21 Kb.
ABSTRACT
Objective: research aimed at describing the results of the use of thymoglobulin inducing therapy or basiliximab in patients transplanted at the Institute of Nephrology during 2014.
Method: A descriptive study was carried out in a series of cases for evaluation of technology, from January 2014 to May 2015 in the Transplant Service of the Institute of Nephrology. Universe consisted of 51 patients from a living or cadaveric donor. Creatinine levels were taken into account during the first, third and sixth months after transplantation. The default limit of follow-up was until May 31, 2015, which establishes a maximum observation period of 17 months, which was taken as reference in the survival study. With this date the state of last news of the renal graft and the free interval of acute rejection was determined.
Results: patients between 40 and 59 years old (52.9 %) and male patients (70.6 %) predominated. The most commonly used type of induction was the thymoglobulin scheme. At one year, the infection rate was 30%, the graft rejection rate was 20.6 %, the graft survival rate was 84.3 % and the patient survival rate was 96.1 %.
Conclusions: the therapeutic results were good, low rates of infection and acute rejection were found, with adequate graft and patient survival, with comparable results with both types of induction.
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