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2017, Number 1

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Rev Cubana Pediatr 2017; 89 (1)

Comparative evaluation between the non-HDL cholesterol and LDL cholesterol in children and adolescents

Cuartas S, Pérez TM

Language: Spanish
References: 20
Page: 20-29
PDF size: 159.50 Kb.


ABSTRACT

Introduction: non-HDL cholesterol (non-HDL) has been identified as a significant predictor of the existence of atherosclerosis and persistent dyslipidemia.
Objective: to determine the prevalence of increased non-HDL cholesterol with respect to the LDL cholesterol as well as their correlation with other lipid parameters and to underscore the advantages of their use in pediatrics.
Methods: a retrospective observational study was conducted in private pediatric physician´s offices for 15 years. Nine hundred and forty one patients were studied in terms of age, sex, body mass index and lipid profile. The cutoff point for non-HDL cholesterol was · 145 mg/dL, and for the LDL cholesterol · 130 mg/dL.
Results: the non-HDL cholesterol allowed detecting 26 patients (2.7 % higher) among those with increased LDL cholesterol. Statistically significant differences for all the analyzed risk factors were observed in the increased non-HDL cholesterol group, more prevalent in females and in the three age groups (p ‹ 0.05).
Conclusions: the collected data support the proposal of using non-HDL cholesterol as a parameter to identify patients with future cardiovascular risks because of its simplicity and specificity; however, more studies are needed to establish its advantages.


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