2017, Number 1
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Bol Clin Hosp Infant Edo Son 2017; 34 (1)
Enfermedad Mixta del Tejido Conectivo de inicio en la Infancia
Suárez LLM
Language: Spanish
References: 8
Page: 44-47
PDF size: 306.79 Kb.
ABSTRACT
Mixed Connective Tissue Disease (MCTD) is a disease whose manifestations include clinical features of several autoimmune
diseases, including: systemic lupus erythematosus, juvenile idiopathic arthritis, dermatomyositis/polymyositis and
systemic sclerosis. The diagnosis is made by associating these manifestations with the presence of hight titers of antibodies
against ribonucleoproteins. The prognosis depends on the predominant organic condition and the treatment should
be directed to the control of these symptoms.
REFERENCES
1.- Berard RA, Laxer RM. Pediatric mixed connective tissue disease. Curr Rheumatol Rep. 2016; 5: 18-28.
2.- Kasukawa R, Sharp GC. Mixed connective tissue disease and antinuclear antibodies. Ámsterdam: Elsevier 1987; 41-47.
3.- Petty R, Laxer R, Lindsley C, Cassidy J. Textbook of pediatric rheumatology. Philadelphia: Elsevier, 2011.
4.- Burdt MA et al. Long-term outcome in mixed connective tissue disease: longitudinal clinical and serologic findings. Arthritis Rheum. 1999; 42: 899-909.
5.- Venables PJW. Mixed connective tissue disease. Lupus. 2006; 15: 132-137.
6.- Mier RJ, Shishov M, Higgins GC et al. Pediatric-onset mixed connective tissue disease. Rheum Dis Clin North Am. 2005; 31: 483-496.
7.- Pope J. Other manifestations of mixed connective tissue disease. Rheum Dis Clin North Am. 2005; 31: 519- 533.
8.- Ying Y, Hsu Y, Hui H et al. Fifteen-year experience of pediatric-onset mixed connective tissue disease. Clin Rheumatol. 2010; 29: 53-58.