López MA

Language: Spanish
References: 22
Page: 14-19
PDF size: 315.89 Kb.

ABSTRACT

Iron overload is rare in the neonatal age, and can be related to serious complications. In the Neonatal Intensive Care Unit (NICU), transfusion of erythrocyte concentrate is a common intervention, making them susceptible to iron overload when the patient is exposed to three or more transfusions of this blood derivative. The incidence of this entity in neonates has been a little explored in Mexico. Patients admitted to the NICU who had more than three transfusions during their hospitalization where included. Follow-up was carried out until he was discharged, where serum ferritin and liver function tests were taken. Of the patients admitted to the NICU for one year, 17.8% required transfusion, 19 patients required more than three transfusions, and 15 patients were included in the study. Of the 15 patients, 7 required more than 3 transfusions, with the mean number of transfused red cells being 4. The 26.6% of patients had serum ferritin levels greater than 1000ng / ml, serum ferritin levels in neonates had no correlation with the amount of transfused milliliters, transaminase levels, lactic dehydrogenase, bilirubin, and alkaline phosphatase. No correlation was found between ferritin levels and the number of milliliters or number of transfused red cell concentrates. These results differ from those found in the literature, probably explained by the small number of samples that will need to be increased.

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