Prado SA, Rodríguez RAA, Ocampo GA

Language: Spanish
References: 22
Page: 101-105
PDF size: 85.84 Kb.

ABSTRACT

The melanocytoma is a benign lesion caused by proliferation of melanocytes normally found in the uvea. They can occur anywhere along the uveal tract, although the optic disc is the most common site. With a low incidence, it usually has a unilateral presentation in hyper-pigmented adults and is asymptomatic, stationary and rarely undergoes a malignant transformation. Melanocytomas are uniform densely hyper-pigmented isolated lesions that may present pigment dispersion and secondary elevated IOP. They have a strong tendency to undergo necrosis and fragmentation simulating a melanoma with hyphema, ectopia or glaucoma.
In the current paper we describe the clinical, echographical and pathologic characteristics of a case of iris melanocytoma that mimicked melanoma.

REFERENCES

1. 1. Zimmerman LE, Garron LK. Melanocytoma of the optic disc. Int Opthalmol Clin 1962; 2:431-40.

2. 2. Boniuk M. Ocular and Anexal Tumors: New and Controversial Aspects. Symposium Sponsored by Departament of Ophtal-

3. mology, Baylor University College of Medicine. St. Louis: Mosby, 1964; 385.

4. 3. Shields JA, Font RL. Melanocytoma of the Choroid Clinically simulating a malignant melanoma. Arch Ophtalmol 1972; 87:396-400.

5. 4. Lee JS, Smith RE, Minckler DS. Scleral Melanocytoma. Ophthalmology 1982; 89:178-82.

6. 5. Verdaguer J, Valenzuela H, Strozzi L. Melanocytoma of the conjunctiva. Arch Ophthalmol 1974; 91:363-6.

7. 6. Howard GM, Forrest AW. Incidence and location of Melanocytomas. Arch Ophthalmol 1967; 77:61-6.

8. 7. Apple D, Boniuk M. Clinical Pathologic Review of a Melanotic Lesion. Survey of Ophthalmology 1998; 42:4.

9. 8. LoRusso F, Boniuk M, Font R. Melanocytoma (Magnocellular Nevus) of the Ciliry Body: Report of 10 cases and review of the literature. American Academy of Ophthalmology. Elsevier Science Inc. 2001:795-800.

10. 9. Jakobiec FA, Silbert G. Are most Iris “melanomas” really nevy? A Clinicopathologic study of 189 lesions. Arch Ophthalmol 1981; 99:2117-32.

11. 10. Stokes DW, ODay DM, Glick AD. Melanocytoma of the Ciliary Body with Scleral Extension. Ophthalmic Surgery Laser, 1993; 24: 200-202.

12. 11. Sinisterra-Pava JP, Salcedo-Casillas G, Moragrega-Adame E, Gómez-Leal A, Rodríguez-Reyes AA. Melanocitoma del cuerpo ciliar. Informe de un caso. Rev Mex Oftalmol 2002; 76(5):197-201.

13. 12. Adenis JP, Loubet A, Leboutet MJ, Loubet RA. Melanocytoma of the iris and ciliary body and multiple pigmented tumors ultra structural study. J Fr Ophthal, 1983; 6:257-65.

14. 13. Shields JA, Eagle RC Jr, Shields CL, Nelson LB. Progressive growth of an iris melanocytoma in a child. Am J Ophthalmol, 2002; 133:222-223.

15. 14. Zimmerman LE. Malignant melanoma arising in melanocy-

16. toma of the optic disc. Presented at the Verhoeff Society. Washington, 1975.

17. 15. Tasman W, Jaeger E. Duane’s Clinical Ophthalmology. Lippincott Williams and Wilkins. 2003.

18. 16. Grossniklaus HE. Fine–needle aspiration biopsy of the iris. Arch Ophthalmol 1992; 90:969- 976.

19. 17. Rummelt V, Naumann GOH, Folberg R, Weingeist TA. Surgical management of melanocytoma of the ciliary body with extrascleral extension. Am J Ophthalmol 1994; 117:169-176.

20. 18. Roth AM. Malignant Chance in the melanocytomas of the uveal tract. Surv Ophthalmol 1978; 22:404-12.

21. 19. Yanoff M, Scheie HG. Melanocytic glaucoma: report of a case. Arch Ophthalmol 84:471- 473,1970.

22. 20. The Eye MD. Association Ophthalmic Pathology and Intraocular Tumors. Basic and Clinical Science Course, American Academy of Ophthalmology. 2003-2004 (4).