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ISSN 0028-3851 (Print)

2002, Number 3

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Rev Neurol Neurocir Psiquiat 2002; 35 (3)

Major depression and menopause. A controlled study

Lara TH, Bravo LM, Meléndez MJD, Gutiérrez CE

Language: Spanish
References: 33
Page: 138-143
PDF size: 148.30 Kb.


ABSTRACT

Background. menopause depression constitutes one of the biggest psychopathologic problems in our country, few studied and frequently overruled.
Objective. to explore characteristics of patients with major depression and menopause as compared with patients with major depression without endocrinal disorders.
Methods. Considered clinical characteristics of female patients with diagnosis of major depression according DSM IV criteria during the period of menopause, we studied 60 women with this diagnosis divided in two groups: One with menopause symptoms, and other without them.
Results. Both groups have similar data in DSM IV criteria and similar ratings in Zung ADS, nevertheless have differences in MMPI profiles, where the menopause group show hysterical profiles, and more antecedents of premenstrual tension, with higher correlation with estrogens levels during perimenopause stage, and vasomotor symptoms.
Conclusions. These elements are relevant for differential diagnosis and substitutive hormonal treatment in conjunction with antidepressants.


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