2017, Number 2
<< Back Next >>
Acta Med Cent 2017; 11 (2)
El zinc y el cobre: micronutrientes esenciales para la salud humana
Taboada LN
Language: Spanish
References: 39
Page: 79-89
PDF size: 206.18 Kb.
ABSTRACT
Micronutrients such as Zinc and Copper are molecules present in the human organism in very tiny amounts. The most susceptible persons to have their deficiency are babies, children, teenagers, pregnant women and those women at reproductive age. Deficiency of these elements in children and young people is caused by low consumption of animal’s origin foods or due to a very rich in cereals diet, which contain high level of phitates. Clinical manifestations on adult people mainly had been described in those patients who had intravenous nutrition with very few concentrations of these micronutrients, in patients with very important looses of gastrointestinal fluids or chronic dialyzed people as well as burned or renal dysfunction patients. Main alimentary sources of these micronutrients are shellfish, seafood, red meat and dairy derivatives, fish, peas and lentils. We should keep in mind that cereals inhibit their absorption.
REFERENCES
Terrin G, Berni Canani R, Di Chiara M, Pietravalle A, Aleandri V, Conte F, et al. Zinc in early life: a key element in the fetus and preterm neonate. Nutrients [Internet]. 2015 [citado 2 Sept 2016];7(12):10427-46. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/26690476
González HF, Visentin S. Micronutrientes y neurodesarrollo: actualización. Arch Argent Pediatr [Internet]. 2016 [citado 2 Sept 2016];114(6):[aprox. 10 p.]. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_abstract&pid=S0325-00752016000600016
Prasad AS. Zinc is an antioxidant and anti-inflammatory agent: its role in human health. Front Nutr [Internet]. 2014 [citado 2 Sept 2016];1:14. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429650/
Colmenares Ávila AC, Romano Innaurato FE. Estado nutricional antropométrico y niveles plasmáticos de Hierro, Cobre y Zinc en niños en edad preescolar de la Etnia Añú de La Laguna de Sinamaica. Antropo [Internet]. 2016 [citado 2 Sept 2016];35:19-31. Disponible en: http://www.didac.ehu.es/antropo/35/35-03/Romano.pdf
Borja-Magno A, Mujica-Coopman MF, Pizarro FA, Olivares GM. Estado nutricional de hierro, cobre y zinc en relación con el uso de método anticonceptivo hormonal. Rev Chil Nutr [Internet]. 2014 [citado 2 Sept 2016];41(3):[aprox. 10 p.]. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182014000300011
Wu W, Bromberg PA, Samet JM. Zinc ions as effectors of environmental oxidative lung injury. Free Radic Biol Med [Internet]. 2013 [citado 2 Sept 2016];65(11):57–69. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23747928
Mehmet A, Hilal A, Dilek O, Ferruh A, Abdullah G, Murat C, et al. Efectos del mantenimiento de varias anestesias sobre los niveles séricos de selenio, cobre, cinc y hierro y la capacidad antioxidante. Rev Bras Anestesiol [Internet]. 2015 [citado 2 Sept 2016];65(1):51-60. Disponible en: http://www.sciencedirect.com/science/article/pii/S2255496314000920
Bonaventura P, Benedetti G, Albarède F, Miossec P. Zinc and its role in immunity and inflammation. Autoimmun Rev [Internet]. 2015 [citado 2 Sept 2016];14(4):277–85. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25462582
Grandy G, Weisstaub G, López de Romaña R. Deficiencia de hierro y zinc en niños. Rev Bol Ped [Internet]. 2010 [citado 2 Sept 2016];49(1):[aprox. 8 p.]. Disponible en: http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S1024-06752010000100005
Barbarán E, Vela D. El zinc: un elemento esencial para la vida. Agenda Viva [Internet]. 2016 [citado 2 Sept 2016];1:14-19. Disponible en: https://revistas.ulima.edu.pe/index.php/AgendaViva/article/view/947/899
Li SO, Wang JL, Bjørklund G, Zhao WN, Yin CH. Serum copper and zinc levels in individuals with autism spectrum disorders. Neuroreport [Internet]. 2014 [citado 2 Sept 2016];25(15):1216-20. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25162784
Bjorklund G. The role of zinc and copper in autism spectrum disorders. Acta Neurobiol Exp [Internet]. 2013 [citado 2 Sept 2016];73(2):225-36. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23823984
Griffin IJ, Domellöf M, Bhatia J, Anderson DM, Kler N. Zinc and copper requirements in preterm infants: an examination of the current literature. Early Hum Dev [Internet]. 2013 [citado 2 Sept 2016];89 Suppl 2:S29-34. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/23998450
González-Tarancón R, Calvo-Ruata L, Aramendía M, Ortega C, García-González E, Rello L. Serum copper concentrations in hospitalized newborns. J Trace Elem Med Biol [Internet]. 2017 [citado 2 Sept 2016];39:1-5. Disponible en: http://www.sciencedirect.com/science/article/pii/S0946672X16301171
Syam A, Palutturi S, Djafar N, Astuti N, Razak Thaha A. Micronutrients and growth of children: a literature review. Internat J Med Science Public Health [Internet]. 2016 [citado 2 Sept 2016];5(10):1981-86. Disponible en: http://www.ejmanager.com/mnstemps/67/67-1465282619.pdf
Robledo-Aceves M, Bobadilla-Morales L, Mellín-Sánchez EL, Corona-Rivera A, Pérez-Molina JJ, Cárdenas-Ruiz JJ, et al. Prevalence and risk factors for gastroschisis in a public hospital from west México. Congenit Anom (Kyoto) [Internet]. 2015 [citado 2 Jun 2016];55(2):73-80. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/25243388
Barseghyan K, Aghajanian P, Miller DA. The prevalence of preterm delivery in pregnancies complicated with fetal gastroschisis. Arch Gynecol Obstet [Internet]. 2012 [citado 2 Sept 2016];286(4):889-92. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22660889
Organización Mundial de la Salud. Anomalías congénitas [Internet]. 2015 Abr [citado 2 Jul 2016];370. Disponible en: http://www.who.int/mediacentre/factsheets/fs370/es/
Brindle ME, Flageole H, Wales PW. Influence of maternal factors on health outcomes in gastroschisis: a Canadian population-based study. Neonatology [Internet]. 2012 [citado 2 Sept 2016];102(1):45-52. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22507959
Cengiz B, Söylemez F, Oztürk E, Cavdar AO. Serum zinc, selenium, copper, and lead levels in women with second-trimester induced abortion resulting from neural tube defects: a preliminary study. Biol Trace Elem Res [Internet]. 2004 [citado 22 Feb 2016];97(3):225-35. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/14997023
Hammouda SA, Abd Al-Halim OA, Mohamadin AM. Serum levels of some micronutrients and congenital malformations: a prospective cohort study in healthy Saudi-Arabian first-trimester pregnant women. Int J Vitam Nutr Res [Internet]. 2013 [citado 2 Sept 2016];83(6):346-54. Disponible en: http://econtent.hogrefe.com/doi/abs/10.1024/0300-9831/a000176
Abass RM, Hamdan HZ, Elhassan EM, Hamdan SZ, Ali NI, Adam I. Zinc and copper levels in low birth weight deliveries in Medani Hospital, Sudan. BMC Res Notes [Internet]. 2014 [citado 2 Sept 2016];7:386. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081538/
Terrin G, Berni Canani CR, Passariello A, Messina F, Conti MG, Caoci S, et al. Zinc supplementation reduces morbidity and mortality in very-low-birth-weight preterm neonates: A hospital-based randomized, placebo-controlled trial in an industrialized country. Am J Clin Nutr [Internet]. 2013 [citado 2 Sept 2016];98(6):1468-74. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/24025633
Ram Kumar TV, Ramji S. Effect of zinc supplementation on growth in very low birth weight infants. J Trop Pediatr [Internet]. 2012 [citado 12 Oct 2016];58(1):50–54. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/21546443
Wulf K, Wilhelm A, Spielmann M, Wirth S, Jenke AC. Frequency of symptomatic zinc deficiency in very low birth weight infants. Klin Padiatr [Internet]. 2013 [citado 2 Sept 2016];225(1):13-7. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/22821297
McDonald CM, Manji KP, Kisenge R, Aboud S, Spiegelman D, Fawzi WW, et al. Daily zinc but not multivitamin supplementation reduces diarrhea and upper respiratory infections in Tanzanian Infants: a randomized, double-blind, placebo-controlled clinical trial. J Nutr [Internet]. 2015 [citado 2 Sept 2016];145(9):2153–2160. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548161/
Tabrizi FM, Pakdel FG. Serum level of some minerals during three trimesters of pregnancy in Iranian women and their newborns: a longitudinal study. Ind J Clin Biochem [Internet]. 2014 [citado 2 Sept 2016];29(2):174-180. Disponible en: http://link.springer.com/article/10.1007/s12291-013-0336-x
De la Hoz FE, Santiago LO. Anemia en el embarazo, un problema de salud que puede prevenirse. Rev Med UIS [Internet]. 2014 [citado 29 Sept 2016];26(3):[aprox. 11 p.]. Disponible en: http://revistas.uis.edu.co/index.php/revistamedicasuis/article/view/3920/4380
Arango CM. Evaluación de la efectividad de un programa de atención integral a madres gestantes y niños menores de un año en la reducción de la incidencia de bajo peso al nacer y las deficiencias de micronutrientes. Medellín 2012-2013. Rev Fac Nac Salud Pub [Internet]. 2016 [citado 2 Sept 2016];30(4):61-64. Disponible en: http://www.redalyc.org/pdf/120/12025811024.pdf
Padrón Herrera M, Fernández Regalado R, De la Osa Fernández R, Bacallao Gallestey J, Reboso Pérez J, Martín González I. Estado de nutrición de oligoelementos durante el embarazo: efecto de la suplementación con hierro sobre el estado de nutrición de cinc. Rev Cubana Aliment Nutr [Internet]. 1995 [citado 2 Jun 2016];9(1):[aprox. 4 p.]. Disponible en: http://bvs.sld.cu/revistas/ali/vol9_1_95/ali04195.htm
Weisstaub AR, Menéndez AM, Montemerlo H, Pastene H, Piñeiro A, Guidoni ME, et al. Zinc plasmático, cobre sérico y zinc y cobre eritrocitarios en adultos sanos de Buenos Aires. Acta Bioquím Clín Latinoam [Internet]. 2008 [citado 15 May 2016];42(3):[aprox. 12 p.]. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0325-29572008000300002
Shenkin A. Trace elements and vitamins in parenteral and enteral nutrition. En: Sobotka L. Basics in clinical nutrition. 2nd ed. Praga: Galen; 2011. p. 66-67.
Rubio C, González Weller D, Martín-Izquierdo RE, Revert C, Rodríguez I, Hardisson A. El zinc: oligoelemento esencial. Nutr Hosp [Internet]. 2007 [citado 2 Sept 2016];22(1):[aprox. 10 p.]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112007000100012
Kambe T, Tsuji T, Hashimoto A, Itsumura N. The physiological, biochemical, and molecular roles of zinc transporters in zinc homeostasis and metabolism. Physiol Rev [Internet]. 2015 [citado 2 Sept 2016];95(3):749-84. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/26084690
Durán AS, Ulloa AA, Reyes GS. Comparación del consumo de vitaminas y minerales en adultos mayores chilenos según estado nutricional. Rev Méd Chile [Internet]. 2014 [citado 2 Sept 2016];142(12):[aprox. 10 p.]. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872014001200013
Pizarro AF, Olivares GM, Kain J. Hierro y zinc en la dieta de la población de Santiago. Rev Chil Nutr [Internet]. 2005 [citado 2 Sept 2016];32(1):[aprox. 12 p.]. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182005000100002
Gernand AD, Schulze K, Stewart CP, West KP, Christian P. Micronutrient deficiencies in pregnancy worldwide: health effects and prevention. Nat Rev Endocrinol [Internet]. 2016 [citado 2 Sept 2016];12(5):274-89. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/27032981
Borja-Magno A, Mujica-Coopman MF, Pizarro Aguirre F, Olivares Grohnert M. Efecto de la suplementación combinada con hierro y zinc sobre el estado nutricional de cobre en mujeres de edad reproductiva. Rev Chil Nutr [Internet]. 2014 [citado 2 Sept 2016];41(4):[aprox. 12 p.]. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182014000400007
Ramírez MEV, Marín BEL, Henao MVA, García SIS. Papilla de arroz instantánea para niños de 12 a 36 meses fortificada con micronutrientes: una alternativa para la alimentación infantil. J Eng Technol. 2014;1(2):248-259.