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2016, Number 2

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RCAN 2016; 26 (2)

Repercussion of tumor reduction upon nutritional status of the patient

Guedes RD, León PDO, Pedroso GT

Language: Spanish
References: 47
Page: 224-238
PDF size: 470.71 Kb.


ABSTRACT

Rationale: Tumor reduction might affect the patient´s nutritional status, as well as to unchain the onset of nutritional disorders. Once present, malnutrition might be the cause of complications, and reduced effectiveness of therapeutic response. Objective: To determine the repercussion tumor-reducing treatment upon patient´s nutritional status. Study design: Prospective, longitudinal, with two crosssectional interventions. Study serie: Twenty-nine patients (Males: 69.0%; Average age: 63.5 ± 11.9 years; Tumor´s prevailing location: Digestive tube: 55.2%; Disease stage: Stage IV: 41.4%; Prior surgery: 31.0%) assisting to the Outpatient Clinic, Clinical Nutrition Service, “Dr. Luis Díaz Soto” Hospital (Havana city, Cuba); as part of a tumor-reducing chemotherapy protocol between August 2014 and August 2015. Results: Eighteen patients completed the tumor-reducing treatment. Survival rate was 79.3%. On inclusion in the study, status of nutritional indicators was as follows (in decreasing order): Midarm circumference ‹ Cut-off point: 34.5%; Lymphocytes Global Count ‹ 1500 cells.mm-3: 24.1%; serum Cholesterol: 24.1%; serum Albumin: 24.1%; and Body Mass Index (BMI) ‹ 18.5 Kg.m-2: 17.2%; respectively. Tumorreducing chemotherapy (co-administered with radiotherapy or not) did not significantly affect the behavior of nutritional indicators used when the study serie was restricted to those completing the treatment. Conclusions: Tumor reduction does not affect the nutritional status of those patients completing a prescribed chemotherapy protocol.


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