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ISSN 1028-4818 (Electronic)

2016, Number 6

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Mul Med 2016; 20 (6)

Risk factors in Alzheimer disease in Bayamo municipality

Calzado SR, Fernández CYN

Language: Spanish
References: 24
Page: 24-39
PDF size: 274.25 Kb.


ABSTRACT

Introduction: Alzheimer disease is a problem for the family and for health national systems, due to a lack of treatment and the burden it represents.
Objective: to determine the association of some risk factors with Alzheimer disease from November 2013 to January 2015, Bayamo municipality.
Method: a Cases and controls study. A sample of 35 cases and 64 controls was estimated. Age, skin color, place of residence, occupation, level of schooling, smoking habits, coffee consumption, alcoholism, hypertension, diabetes mellitus, dyslipidemia, personal pathological history of cranial trauma, deterioration of cognitive impairment, depression, anxiety, physical inactivity and obesity.
Results: the univariate analysis showed that age greater than or equal to 70 years almost doubles the risk of Alzheimer's disease, as well as smoking and coffee consumption that double the risk of suffering from the disease. Hypertension and dyslipidemia had the same behaviors. In the analysis of the binary logistic regression model we found that cranioencephalic trauma followed by mild cognitive impairment, depression and arterial hypertension showed an independent, statistically significant and important relation with the risk of Alzheimer's dementia.
Conclusions: the values obtained by adjustment of the logistic regression function that were most associated with the risk factors in Alzheimer's dementia were head injury, mild cognitive impairment, depression and arterial hypertension.


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