2017, Number 02
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MediSan 2017; 21 (02)
Oncospecific therapies in patients with herpes simplex virus
Estrada PGA, Díaz FJM, Márquez FM, Agüero DLA
Language: Spanish
References: 12
Page: 165-172
PDF size: 443.03 Kb.
ABSTRACT
A descriptive and cross-sectional study of 25 patients with cancer infected by the oral herpes simplex virus was carried out. They had the immunologic system damaged due to oncospecific treatment, assisted in the stomatological service of the Specialties Polyclinic of "Saturnino Lora Torres" Teaching Clinical Surgical Provincial Hospital in Santiago de Cuba, from January, 2014 to the same month in 2016, in order to evaluate the results of the clinical and cytopathologic diagnosis of this disorder. In the case material the male sex and pain as clinical symptomatology, the vermilion of the lower lip as the place of more incidence and chemotherapy as the therapeutic modality of this viral agent higher reactivation prevailed. The exfoliative cytology confirmed the presence of multinucleous giant epithelial cells with bodies of intranuclear inclusions and infected cells necrosis, respectively, being these the most significant microscopic findings.
REFERENCES
Monzón J, Acuña M, Canga E, Ortega S. Prevalencia del herpes virus en bolsas periodontales de pacientes asistidos en la Cátedra de Periodoncia de la F.O.U.N.N.E. 2011; 34:36-49.
Rodríguez M, Manriquez X, Rojas IG, Fernández E, Bretahuer U, Sepúlveda E. Estudio comparativo: prevalencia patologías bucales en pacientes pediátricos oncológicos 1997-2007. Int J Odontostomat. 2010 [citado 5 Jul 2016]; 4 (2). Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-381X2010000200008
Miller CS, Danaher RJ. Asymptomatic shedding of herpes simplex virus (HSV) in the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008; 105 (1):43-50.
Gutiérrez de la Peña J. Montis Suau A. Mujer joven con vesículas agrupadas en labio inferior. Med Balear. 2009; 24 (2): 47-8.
Subramaniam P, Babu KL, Nagarathna J. Oral manifestations in acute lymphoblastic leukemic children under chemotherapy. J Clin Pediatric Dent. 2008; 32 (4): 319-24.
Reyes Romero H, Navarro Rojas P, Porta González L, Palmero Klein K, Reyes Barrios H. Actualización en infecciones por el virus herpes simplex. INFORMED. 2012; 14(8):373-89.
Chiarelli M, Rau LH, Scortegagna A. Acute herpetic gingivostomatitis. Report of a case. Rev Odont. 2008; 16 (32):20-2.
Fatahzadeh M, Schwartz RA. Human herpes simplex virus infections: Epidemiology, pathogenesis, symptomatology, diagnosis and management. Journ Am Acad Dermatol. 2007; 57 (5):737-63.
Bernal Cepeda LJ, Ávila Adarme LV, Marín Gallón LM, Casas Martínez JA, Bohórquez Ávila S del P, Barrientos Sánchez S, et al. Detección de la presencia del antígeno y ADN del virus de herpes simple tipo 1 en ganglios trigeminales humanos. Univ Odontol. 2012; 31 (66):115-23.
10.Nicolle MP, Proenca JT, Efstathiou S. The molecular basis of herpes simplex virus latency. Microbiol Rev. 2012; 36: 684-705.
11.Méndez-Tovar LJ, Arévalo-López A, Arroyo-López H. Ulceras cutáneas por coinfección: virus del herpes simple e Histoplasma capsulatum. Dermatol Rev Mex. 2012; 56 (2): 137-140.
12.González Manrique G, Yucumá Gutiérrez S, Bobadilla EJ. Mielitis transversa asociada a virus herpes tipo 1. Acta Neurol Colomb. 2013 [citado 5 Jul 2016]; 29 (3). Disponible en: http://www.scielo.org.co/scielo.php? script=sci_arttext& pid=S0120-87482013000300009