2016, Number 6
<< Back Next >>
Rev Med Inst Mex Seguro Soc 2016; 54 (6)
Standardization of gastric emptying scintigraphy with egg white labeled with 99mTc-sulfur colloid
Contreras-Contreras K, Villanueva-Pérez RM, Menez-Díaz DG, Iwasaki-Otake LE, González-Díaz JI, Mendoza-Vásquez RG
Language: Spanish
References: 15
Page: 746-751
PDF size: 300.88 Kb.
ABSTRACT
Background: Gastric emptying scintigraphy has become the gold standard,
by excellence, in gastric emptying studies. This method must be
standardized for the correct interpretation of results. The ideal protocol
must be performed with an egg sandwich or egg white poder, both
labeled with
99mTc sulphur colloid. The aim of this study was to standardize
and determine the protocol with
99mTc sulphur colloid incorporated
in egg white and compare it with a hamburger labeled with
99mTc
sulphur colloid as well.
Methods: We studied 30 patients who underwent gastric emptying scintigraphy
with the two aforementioned meals.
Results: Emptying percentages and retention with both meals were similar
within an hour and two; however, statistical significance arose until
the third hour with a
p value of 0.26 by using Student’s t for independent
samples.
Conclusions: Gastric emptying studies in both protocols where similar
with normal ranges. The egg white ingested must be consistent for reproducible
results in gastric motility disease, like organoleptic and volume
characteristics.
REFERENCES
Maurer AH. Can we prevent tarnishing a gold standard? Semin Nucl Med.1995;25(4):288.
Henkin RE. Nuclear medicine. Second edition. Philadelphia, USA: Mosby Elsevier; 2006. pp. 893-906.
Tougas G, Eaker EY, Abell TL, Abrahamsson H, Boivin M, Chen J, et al. Assessment of gastric emptying using a low-fat meal: establishment of international control values. Am J Gastroenterol. 2000;95(6):1456- 62. doi:10.1111/j.1572-0241.2000.02076.x
Guyton AC, Hall JE. Textbook of Medical Physiology. Eleventh edition. Philadelphia, USA: Elsevier Saunders; 2006.
Minami H, McCallum RW. The physiology and pathophysiology of gastric emptying in humans. Gastroenterology. 1984 Jun;86(6):1592-610.
Morgan KG, Muir TC, Szurszewski JH. The electrical basis for contraction and relaxation in canine fundal smooth muscle. J Physiol. 1981 Feb;311:475-88.
Berger T. Studies on the gastric emptying mechanism in healthy persons and patients after partial gastrectomy. Acta Chir Scand Suppl. 1969;404:1-51.
Makhlouf GM. The neuroendocrine design of the gut. The play of chemicals in a chemical playground. Gastroenterology. Gastroenterology. 1974 Jul;67(1):159-84.
Meyer JH, MacGregor IL, Gueller R, Martin P, Cavalieri R. 99mTc-tagged chicken liver as a marker of solid food in the human stomach. Am J Dig Dis. 1976 Apr;21(4):296-304.
Donohoe KJ, Maurer AH, Ziessman HA, Urbain JL, Royal HD, Martin-Comin J; Society for Nuclear Medicine; American Neurogastroenterology and Motility Society. Procedure guideline for adult solid-meal gastric-emptying study 3.0. J Nucl Med Technol. 2009 Sep;37(3):196-200. doi: 10.2967/ jnmt.109.067843.
Mettler FA, Guiberteau MJ. Essentials of nuclear medicine imaging. Sixth edition. Houston, Texas: Elsevier Saunders; 2012.
Lawal A, Barboi A, Krasnow A, Hellman R, Jaradeh S, Massey BT. Rapid gastric emptying is more common than gastroparesis in patients with autonomic dysfunction. Am J Gastroenterol. 2007 Mar;102(3):618-23.
Guo JP, Maurer AH, Fisher RS, Parkman HP. Extending gastric emptying scintigraphy from two to four hours detects more patients with gastroparesis. Dig Dis Sci. 2001 Jan;46(1):24-9.
Ziessman HA, Bonta DV, Goetze S, Ravich WJ. Experience with a simplified, standardized 4-hour gastric-emptying protocol. J Nucl Med. 2007 Apr;48(4):568-72.
Bennink R, Peeters M, van den Maegdenbergh V, Geypens B, Rutgeerts P, De Roo M, et al. Comparison of total and compartmental gastric emptying and antral motility between healthy men and women. Eur J Nucl Med. 1998;25:1293-9.
Full text