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2016, Number 3

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VacciMonitor 2016; 25 (3)

Rotavirus vaccines: current status and future trends

Amin BN, Fernández CS

Language: Spanish
References: 58
Page: 89-97
PDF size: 123.61 Kb.


ABSTRACT

Prior to the introduction of rotavirus vaccines in 2006, this pathogen was the leading cause of gastroenteritis among children under fi ve years old of the entire world. Vaccines are a principal strategy to protect children against severe rotavirus gastroenteritis. There are currently two vaccines commercially available Rotarix® and RotaTeq® and their administration is having a signifi cant impact on the reduction in rotavirus hospitalizations and ambulatory consultations. However, the cost of supporting a national immunization program for poor countries is relatively high. There is also the concern that the vaccine may lead to the selection and spread of new strains antigenically different, decreasing the vaccine effi cacy. In order to solve these issues some vaccine manufacturers are developing new vaccines such as ROTAVAC® licensed for use in India. Health authorities in several countries have implemented monitoring programs in sentinel hospitals to follow hospitalization due to rotavirus gastroenteritis and to conduct studies to evaluate the effectiveness and impact of the vaccine.


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