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Órgano oficial de difusión de la Federación Mexicana de Patología Clínica, AC y de la Asociación Latinoamericana de Patología Clínica/Medicina de Laboratorio

2004, Number 4

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Rev Mex Patol Clin Med Lab 2004; 51 (4)

Breath test in the diagnosis of infection with Helicobacter pylori

Barriga AG, Arumir EC, Mercado GF

Language: Spanish
References: 22
Page: 194-199
PDF size: 58.80 Kb.


ABSTRACT

Objective: Determine the diagnostic value of 13 C–Urea breath test (Breath Tek UBIT, Meretek, Co, Lafayette, Co, USA) TM in the diagnosis of Helicobacter pylori infection in pediatric and adults patients with probably peptic ulcer disease. Methods: 13C-Urea breath test and histopathological study of a biopsy obtained by esophago-gastroduodenoscopy was performed in 108 pediatric and adult patients using an infrared spectrometer (UBIT-IR-300 Photal, Otsuka Japan) TM. The obtained results was statistical analyzed by X2 test, U of Fisher, Mann-Whitney and Spearman. Results: Non statistically significative differences were found with the breath test by: sex, age or value distribution of results The 13-C Urea breath test shown a 100% of sensitivity and specificity compared with the biopsy results. Conclusions: The 13-C urea breath test was very accurate in the differential diagnosis of Helicobacter pylori infection, and in the confirmation of erradication after a course of a antimicrobial therapy, in pediatric and adult patients. Besides, the urea breath test was a quick on-site analysis (less 20 minutes) easy to do, and the instrument simple to operate.


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