2016, Number 4
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Rev Hematol Mex 2016; 17 (4)
Invasive aspergillosis in patients given allogeneic stem cell transplants: Epidemiology, diagnosis, prophylaxis and treatment
Cruz-Contreras DG
Language: Spanish
References: 16
Page: 262-267
PDF size: 418.99 Kb.
ABSTRACT
Invasive aspergillosis remains as one of the most important causes
of morbidity and mortality in allogeneic stem cell transplantation
(alloSCT) recipient patients. The risk of acquiring this kind of invasive fungal infection depends on multiple factors, prolonged neutropenia
and immunosuppression are the most important of them. Invasive
aspergillosis is characterized by any organ or tissue invasion, lungs
are the most often affected (pulmonary aspergillosis). The incidence
of invasive aspergillosis has decreased in the last years due to routine
inclusion of diagnosis tests and prophylactic drugs in transplant protocols
in worldwide hospitals. Despite the above, invasive aspergillosis
has an elevated mortality among patients, this is the reason why it is
important to do a soon diagnosis and thus start aggressive antifungal
treatment.
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