2016, Number 6
Microalbuminuria as a marker of cardiovascular risk in hypertensive patients
Language: Spanish
References: 20
Page: 619-627
PDF size: 507.56 Kb.
ABSTRACT
Background: atherosclerosis is the main cause in the development of heart diseases. A big number of victims, generally healthy, present a deadly cardiovascular event and this is the first clinical manifestation that is detected in atherosclerosis. Microalbuminuria is known as being related to kidney damage in patients with type 1 and type 2 diabetes. It is a potential predictor of heart diseases and has become a marker of atherosclerosis in an early stage.Objective: to determine the utility of microalbuminuria as a marker of cardiovascular risk.
Methods: an observational longitudinal study was conducted, from May 31st 2014, to April 30th 2015 to determine the utility of microalbuminuria in hypertensive patients without kidney vascular dama-ge in health care center 2 of the clinic Tula Aguilera in Camagüey. The universe of study was composed of 66 hypertensive patients without kidney vascular damage, who met the inclusion and exclusion criteria, upon which the study is based. For the analysis and processing of the results descriptive statistics measures were used such as absolute numbers and percentage to describe the studied variables.
Results: the presence of microalbuminuria prevailed in female sex and people over 60 years old. Among the risk factors, sedentarism followed by age over 65 were the most significant. From the analyzed biochemical parameters hipercolesterolemia was higher in number, microalbuminuria was positive with a larger percent in patients with associated heart diseases.
Conclusions: it is considered that microalbuminuria is not only a marker of kidney damage but also an indicator of cardiovascular risk.
REFERENCES
Cooper RS, Ordúñez García P, Iraola Ferrer MD, Bernal Muñoz JL, Espinosa-Brito A. Cardiovascular disease and associated risk factors in Cuba: Prospects for Prevention and Control. Am J Public Health [Internet]. 2006 [cited 2013 Jan 20];96(1):[about 4 p.]. Available from: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1470428/.
Fink HA, Ishani A, Taylor BC, Greer NL, MacDonald R, Rossini D, et al. Screening for, monitoring,and treatment of chronic kidney disease stages 1 to 3: a systematic review for the u.s. Preventive services task force and for an american college of physicians clinical practice guideline. Ann Intern Med. 2012 Apr 17;156(8):570-81.
Tagle Vargas R, González Fuenzalida F, Acevedo Blanco M. Microalbuminuria y excreción urinaria de albúmina en la práctica clínica. Rev méd Chile [Internet]. Jun 2012 [citado 19 Feb 2016];140(6):[aprox. 9 p.]. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0034-98872012000600016&lng=es
Lomelí Estrada C, Rosas-Peralta M, Lorenzo Negrete A, Saucedo-Zeni N. Microalbuminuria y factores de riesgo cardiovascular asociados en pacientes con hipertensión arterial sistémica. Subanálisis del estudio I-Search. Arch Cardiol Méx [Internet]. Jun 2012 [citado 7 Mar 2015];82(2):[aprox. 12 p.]. Disponible en:http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1405-99402012000200004&lng=es
Andrés Arias J, Castaño Castrillón JJ, Duque Moreno LV, Giraldo José F, Alejandro González P, Orlando Mejía C, et al. La microalbuminuria como factor pronóstico en un grupo de pacientes hipertensos de una entidad de primer nivel de atención de Manizales (Colombia), 2010. Salud Uninorte. Ene-Jun 2012;28(1):36-48.
Userpater M, Inserra F. Pérdida de proteínas urinarias como marcador de daño renal no glomerular y de riesgo cardiovascular. Revista de nefrología, diálisis y trasplante. Rev nefrol dial traspl [Internet]. 2004 [citado 12 Feb 2012];24(2):[aprox. 6 p.]. Disponible en: http://renal.org.ar/revista/REVISTA/Rev%20Nefrol%20Dial%20Traspl%202004%2024%282%29.pdf#page=36