2004, Number 1
<< Back Next >>
Med Cutan Iber Lat Am 2004; 32 (1)
Patch Granuloma Annulare. Seven New Cases
García FM, Curcó BN, Pagerols BX, Vives VP
Language: Spanish
References: 21
Page: 23-26
PDF size: 252.35 Kb.
ABSTRACT
Introduction: PPD is the main contact sensitizing agent in hairdressing.
We present a study whose objective has been to establish the real frequency
of positive reactions to PPD, its relevance, and to define the characteristics
of the patients on risk of active sensitization.
Material and methods: We have carried out a 10 -year retrospective
epidemiologic study. During this period patch tests were taken with the
standard battery of GEIDC to a total of 1,878 patients suspected of ACD.
Results: 60.96% of the patched patients presented at least a positive
response. 4.36% of these showed postive to PPD, of which 66% we found
to have a positive relevancy. The most frequent location of the lesions were
the hands (56%). The localization of the lesions in the scalp was
related to the use of capillary dyes that contained PPD. It is surprising the
elevated frequency of positive tests associated to Balsam of Peru (7%)
and fragrances mix (7%). In patients with a positive test to PPD we have found
a statistically significant association between a positive test to PPD
and working activity related with hairdresser shops (p < 0.01; OR: 8.49 with
IC 95%: 3.60 < OR < 19.97).
Conclusion: PPD continues to be a sensitizing agent that is frequent in
our environment, reason why it is important to keep it in the standard
battery. The prototype patient is a female with hand dermatitis, worker or
client of a hairdresser shop, that is sensitized due to the contact to
capillary dyes.
REFERENCES
Dahl MV. Granuloma annulare. In: Fitzpatrick TB, Eisen AZ, Wolf K, Freedberg IM, Austen KF. Dermatology in general medicine. New York, NY: Mc Graw-Hill International Ed Co 1993: 1187-91.
Studer EM, Calza AM, Saurat JH. Precipitating factors and associated diseases in 84 patients with granuloma annulare: a retrospective study. Dermatology 1996; 193: 364-8.
Spencer SA, Fenske NA, Espinoza CG. Granuloma annulare-like eruption due to chronic Epstein-Barr virus infection. Arch Dermatol 1988; 124: 250 -5.
Arnold HL, Odom RB, James WD. Andrew’s: Diseases of the skin. Philadelphia, Pa: WB Saunders Co 1990: 137-310.
Dabski K, Winkelmann RK. Generalized granuloma annulare: Clinical and laboratory findings in 100 patients. J Am Acad Dermatol 1989; 20: 39-47.
Umbert P, Winkelmann RK. Histologic, ultrastructural, and histochemical studies of granuloma annulare. Arch Dermatol 1977; 113: 1681- 6.
Mullans E, Helm KF. Granuloma annulare: an immunohistochemical study. J Cutan Pathol 1994; 21: 135-9.
Friedman-Birnbaum R, Weltfriend S, Munichor M, Lichtig C. A comparative histopathologic study of generalized and localized granuloma annulare. Am J Dermatopathol 1989; 11: 144-8.
Monash S. Granuloma annulare disseminatum. Report of two cases. Arch Derm 1932; 25: 122-31.
Ogino A, Tamaki E. Atypical granuloma annulare. Dermatologica 1978; 156: 97- 100.
Selmanowitz VJ, Vandow JE, Director W. Atypical granuloma annulare. Arch Dermatol 1966; 93: 454- 6.
Eng AM. Erythematous generalized granuloma annulare. Arch Dermatol 1979; 115: 1210 -1.
Sábat M, Bielsa I, Ribera M. et al. Granuloma anular macular. Estudio de cinco casos. Actas Dermosifiliogr 2003; 94: 524-7.
Mutasin DF, Bridges AG. Patch granuloma a nnulare.Clinicopathologic study of 6 patients. J Am Acad Dermatol 2000; 42: 417-21.
Chan LS. Giant inflammatory targetoid plaques. Arch Dermatol 1992; 128: 977-82.
Ackerman AB, White WL, Guo Y, Umbert I. Differential diagnosis in dermatopathology IV. Malvern Pennsylvania: Lea & Febiger Co 1994: 34-7.
Magro CM, Crowson AN, Schapiro BL. The interstitial granulomatous drug reaction: a distinctive clinical and pathological entity. J Cutan Pathol 1998; 25: 72-8.
Perrin C, Lacour JP, Castanet J, Michiels JF. Interstitial granulomatous drug reaction with a histological pattern of interstitial granulomatous dermatitis. Am J Dermatopathol 2001; 23: 295-8.
Tomasini C, Pippione M. Interstitial granulomatous dermatitis with plaques. J Am Acad Dermatol 2002; 46: 892-9.
Magra CM, Crowson AN. Lichenoid and granulomatous dermatitis. Int J Dermatol 2000; 39: 126 -33.
Moguelet P, Vignon-Pennamen MD. Granulomes cutannés palissadiques. Encycl Med Chir. Dermatologie 2003; 98 - 475 -A- 10:10 pag.