2015, Number 4
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Arch Neurocien 2015; 20 (4)
Influence of anxiety and depression on the executive function in patients with multiple sclerosis
Martin-Ramos R, Jiménez-Morales RM, Herrera-Jiménez LF, Guerra-Pérez LR, Martin-Ramos R, Pérez-Medinilla YT
Language: Spanish
References: 29
Page: 233-239
PDF size: 117.56 Kb.
ABSTRACT
Objective: to determine the influence of anxiety and depression on the executive function components in patients
with Multiple Sclerosis (MS).
Methods: thirty patients with MS and 30 healthy controls were assessed through a
battery of cognitive tests, the State-Trait Anxiety Inventory (STAI) and the Beck Depression Inventory (BDI).
Results:
the group of MS presented statistically significant differences (p ‹0.05) in tests that assess inhibitory control,
working memory, cognitive flexibility, abstract reasoning, practical-constructive problem solving, phonetic and verbal
fluency, trait and state anxiety, and depression. The simple linear regression analysis found that high levels of
anxiety and depression may be a predictor of variability in the functioning of inhibitory control, cognitive flexibility,
practical and constructive problem solving, and semantic and verbal fluencies.
Conclusions: the rates of anxiety and
depression significantly influence some components of the executive functions.
REFERENCES
Cabrera-Gómez JA. Guías de práctica clínica. Esclerosis múltiple. La Habana: Cien Méd; 2009.
Amato MP, Zipoli V, Portaccio, E. Multiple sclerosis related cognitive changes: a review of cross-sectional and longitudinal studies. J Neurol Sci 2006;15:41-6.
Amato MP, Portaccio E, Goretti B. Relevance of cognitive deterioration in early relapsing-remitting MS: a 3-year followup study. Mult Scler 2010;16:1474-82.
Chiaravalloti ND, DeLuca J. Cognitive impairment in multiple sclerosis. Lancet Neurol 2008;7:1139-51.
Tirapu-Ustárroz J, García-Molina A, Luna-Lario P, Roig-Rovira T, Pelegrín-Valero C. Modelos de funciones y control ejecutivo. Rev Neurol 2008;5:684-92.
Ardila AR, Solís OF. Desarrollo histórico de las funciones ejecutivas. Rev Neuropsi Neuropsiq Neurocien 2008;8:1-21.
Sastre-Riba S, Merino-Moreno N, Poch-Olivé ML. Formatos interactivos y funciones ejecutivas en el desarrollo temprano. Rev Neurol 2007; 2 (Suppl 2): S61-5.
Benedict RH, Cox D, Thompson LL, Foley F, Weinstock- Guttman B, Munschauer F. Reliable screening for neuropsycholgical impairment in multiple sclerosis. Mult Scler 2004;10:675-8.
Bruce J, Arnet, P. MS patients with depressive symptoms exhibit affective memory biases when verbal encoding strategies are suppressed. J Int Neuropsychol Soc 2005; 11:514-21
Lubrini G, Periáñez JA, Ríos-Lago M, Frank A. Velocidad de procesamiento en la esclerosis múltiple remitente recurrente: el papel de los síntomas depresivos. Rev Neurol 2012;16: 585-92.
Lester K, Stepleman L, Hughes M. The Association of Illness Severity, Self-Reported Cognitive Impairment, and Perceived Illness Management with Depression and Anxiety in a Multiple Sclerosis Clinic Population. J Behav Med 2007; 30:177-86.
Ferreira ML. Cognitive deficits in multiple sclerosis. A systematic review. Arq Neuropsiquiatr 2010; 68:632-41
Poser CM, Paty DW, Scheinberg L. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227-31.
McDonald WI, Compston A, Edan G. Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of MS. Ann Neurol 2001; 50:121-7
Sepulcre J1, Vanotti S, Hernández R. Cognitive impairment in patients with multiple sclerosis using the Brief Repeatable Battery-Neuropsychology test. Mult Scler 2006; 12:187-95.
Heaton R, Chelune G, Talley J, Kay G, Curtiss G. Wisconsin Card Sorting Test Manual. Odessa, Florida: Psychological Assessment Resources; 1993.
Golden CJ. Stroop color and word test. Chicago, IL: Stoelting; 1978.
Giovagnoli AR, Del Pesce M, Mascheroni S, Simoncelli M, Laiacona M, Capitani E. Trial making test: normative values from 287 normal adult constrols. Ital J Neurol Sci 1996; 17:305-9.
Benton AL, Hamsher K. Multilingual aphasia examination. Iowa City: AJA Associates; 1989.
Wechsler D. Escala de inteligencia de Wechsler para adultos. Madrid: TEA: 1999.
Spielberger CD, Edwards C, Lushene R. Montouri J, Platzek D. STAIC preliminary manual. Palo Alto, CA: Consulting Psychologists Press; 1973.
Beck AT, Steer RA. BDI: beck depression Inventory manual. New York: Psychological Corporation. New York: Psychological Corporation; 1987.
Arango-Lasprilla JC, DeLuca J, Chiaravalloti N. El per fil neuropsicológico en la esclerosis múltiple. Psicothema 2007;19:1-6.
Eysenck MW, Derakshan N, Santos R, Calvo MG. Anxiety and cognitive performance: attentional control theory. Emotion 2007; 7:336-53.
Julian LJ, Arnett PA. Relationships among anxiety, depression, and executive functioning in multiple sclerosis. Clin Neuropsychol 2009; 23:794-804.
Byron K, Khazanchi SA. Meta-analytic investigation of the relationship of state and trait anxiety to per formance on figural and verbal creative tasks. Pers Soc Psychol Bull 2011; 37:269-83.
Bol Y, Duits AA. Hupperts RM, Verlinden I, Verhey FR. The impact of fatigue on cognitive functioning in patients with multiple sclerosis. Clin Rehabil 2010; 24:854-62.
Hanssen KT, Beiske AG, Landr NI, Hessen E. Predictors of executive complaints and executive deficits in multiple sclerosis. Acta Neurol Scand 2014; 129:234-42.
Nunnari D, De Cola MC, D’Aleo G, Rifici C, Russo M, Sessa E, et al. Impact of depression, fatigue, and global measure of cortical volume on cognitive impairment in multiple sclerosis. Biomed Res Int 2015;519-785.