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ISSN 0210-5187 (Electronic)

2004, Number 1

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Med Cutan Iber Lat Am 2004; 32 (1)

Contact Dermatitis to Para-Phenylendiamine. A Ten-Year Experience

Fernández VJM, Armario HJC

Language: Spanish
References: 27
Page: 19-22
PDF size: 122.17 Kb.


ABSTRACT

Introduction: PPD is the main contact sensitizing agent in hairdressing. We present a study whose objective has been to establish the real frequency of positive reactions to PPD, its relevance, and to define the characteristics of the patients on risk of active sensitization.
Material and methods: We have carried out a 10 -year retrospective epidemiologic study. During this period patch tests were taken with the standard battery of GEIDC to a total of 1,878 patients suspected of ACD.
Results: 60.96% of the patched patients presented at least a positive response. 4.36% of these showed postive to PPD, of which 66% we found to have a positive relevancy. The most frequent location of the lesions were the hands (56%). The localization of the lesions in the scalp was related to the use of capillary dyes that contained PPD. It is surprising the elevated frequency of positive tests associated to Balsam of Peru (7%) and fragrances mix (7%). In patients with a positive test to PPD we have found a statistically significant association between a positive test to PPD and working activity related with hairdresser shops (p < 0.01; OR: 8.49 with IC 95%: 3.60 < OR < 19.97).
Conclusion: PPD continues to be a sensitizing agent that is frequent in our environment, reason why it is important to keep it in the standard battery. The prototype patient is a female with hand dermatitis, worker or client of a hairdresser shop, that is sensitized due to the contact to capillary dyes.


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