2016, Number 3
Dexmedetomidine endoscopic evaluation of induced sleep in obstructive sleep apnea
Flores-Ochoa JR, Villanueva-Guzmán SI, Macías-Reyes H, Sánchez- Hernández E, Lugo-Saldaña R
Language: Spanish
References: 0
Page: 190-197
PDF size: 252.50 Kb.
ABSTRACT
Background: Nowadays, obstructive sleep apnea affects 6% of females and 13% of males. Diagnosis should be made with caution, with the help of sleep studies, without forgetting the topographic evaluation. First line treatment is positive pressure; however, other options are available, such as surgical ones that need a dynamic evaluation of the airway.Objetive: To evaluate the administration of dexmedetomidine as a sleep inductor; using a bi-spectral index to corroborate the degree of sedation, orienting the patient in different positions.
Material and Method: A study was made evaluating 20 patients with diagnosis of obstructive sleep apnea. We use dexmedetomidine to induce sleep and place patients into two positions, lateral and supine. We monitor physiological readings and bispectral index in three different times, evaluating the capacity of recovery and satisfaction of patients.
Results: We found initial bi-spectral index of 80.2±2.4, during the procedure 62.2±2.8, and at the end of the procedure 98.3±6.7. We did not apply topical anesthesia for any procedure, in every procedure we evaluated obstructive events; the mean time of recovery was of 9.35±1.8 minutes. Drug-induced sleep endoscopy using dexmedetomidine offers duration of 35.05±1.8 minutes, with a 95% satisfaction rate.
Conclusion: Administration of dexmedetomidine by means of infusion and bi-spectral index allows us to induce a sleep capable of imitate the events of patients with obstructive sleep apnea, showing us the primary location of obstruction and the variations of this site depending on the position of the patient. Being able to verify the degree of sedation allows us to use the amount of medication necessary to imitate as much as possible the physiological sleep.