2016, Number 5
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Rev Med Inst Mex Seguro Soc 2016; 54 (5)
Oral squamous cell carcinoma and lichen planus vs. lichenoid lesions. Case report
Esquivel-Pedraza L, Fernández-Cuevas L, Ruelas-Villavicencio AL, Guerrero-Ramos B, Hernández-Salazar A, Milke-García MP, Méndez-Flores S
Language: Spanish
References: 30
Page: 673-679
PDF size: 295.43 Kb.
ABSTRACT
Background: The development of squamous cell carcinoma
from oral lichen planus is controversial. We report a case of
intraoral squamous cell carcinoma, which presents together
with lesions of oral lichen planus. The aim of this report was
to analyze the problem to distinguish between the incipient
changes of squamous cell carcinoma from the features described
in oral lichen planus, in order to establish an accurate
diagnosis of both entities.
Case report: A 57-year old man with a history of smoking and
chronic alcohol intake, who had an ulcerated tumor mass located
in the tongue, and bilateral white reticular patches on buccal
mucosa and borders of the tongue. The histopathological
report was moderately differentiated invasive squamous cell
carcinoma and lichen planus respectively.
Conclusions: The premalignant nature of OLP is still indeterminate
and controversial, this is primarily due to inconsistency
in the clinical and histological diagnostic criteria used to differentiate
cases of oral lichen planus from lichenoid reactions
or other lesions causing intraepithelial dysplasia with high
potentially malignant transformation. Oral lichenoid reactions
are possibly most likely to develop malignant transformation
as compared to the classic OLP lesions.
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